Aberrant DNA replication in cancer
Keywords: بی ثباتی ژنوم ; DNA replication; Translesion DNA synthesis; DNA repair; Genomic instability; Cancer;
مقالات ISI بی ثباتی ژنوم (ترجمه نشده)
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No significant level of inheritable interchromosomal aberrations in the progeny of bystander primary human fibroblasts after alpha particle irradiation
Keywords: بی ثباتی ژنوم ; Genomic instability; Bystander effect; Chromatid break; mFISH; Alpha-particle irradiation
WEE1 inhibition and genomic instability in cancer
Keywords: بی ثباتی ژنوم ; WEE1 kinase; Cancer; Genomic instability; Chromosomal instability; p53; Cell cycle checkpoint
DNA replication timing, genome stability and cancer: Late and/or delayed DNA replication timing is associated with increased genomic instability
Keywords: بی ثباتی ژنوم ; Replication timing; Mutagenesis; Genomic instability
PROBING GENOME MAINTENANCE FUNCTIONS OF HUMAN RECQ1
Keywords: بی ثباتی ژنوم ; Helicase; RecQ; DNA repair; DNA damage; genomic instability
MYCN-mediated overexpression of mitotic spindle regulatory genes and loss of p53-p21 function jointly support the survival of tetraploid neuroblastoma cells
Keywords: بی ثباتی ژنوم ; p53; pRB; Genomic instability; Mitotic catastrophe; Aneuploidy specific lethality genes
Role of genomic instability in arsenic-induced carcinogenicity. A review
Keywords: بی ثباتی ژنوم ; Arsenic; Genomic instability; Chromosomal instability; Microsatellite instability; DNA level instability; Review
Fetal mesenchymal stromal cells from cryopreserved human chorionic villi: cytogenetic and molecular analysis of genome stability in long-term cultures
Keywords: بی ثباتی ژنوم ; array-comparative genomic hybridization; chorionic villi; genomic instability; human placenta; mesenchymal stromal cells
The inhibition of HIF-2α on the ATM/Chk-2 pathway is involved in the promotion effect of arsenite on benzo(a)pyrene-induced cell transformation
Keywords: بی ثباتی ژنوم ; Arsenite; Benzo(a)pyrene; Hypoxia-inducible factor-2α; Genomic instability; Malignant transformation
γH2AX as a marker of DNA double strand breaks and genomic instability in human population studies
Keywords: بی ثباتی ژنوم ; γH2AX; DNA double strand breaks; Genomic instability; Human population studies; Molecular epidemiology
The emerging role of ROS-generating NADPH oxidase NOX4 in DNA-damage responses
Keywords: بی ثباتی ژنوم ; NADPH oxidases; NOX4; Reactive oxygen species (ROS); DNA damage; Genomic instability; Oxidative stress; Inflammation; Cancer;
Chromium and genomic stability
Keywords: بی ثباتی ژنوم ; Chromium; Chromate; Trivalent chromium; Hexavalent chromium; Genomic instability
Translocation capture sequencing: A method for high throughput mapping of chromosomal rearrangements
Keywords: بی ثباتی ژنوم ; Chromosomal translocations; Genomic instability; Activation-induced cytidine deaminase; B lymphocytes; Lymphoma;
Genomic instability and p53 alterations in patients with malignant glioma
Keywords: بی ثباتی ژنوم ; Anaplastic astrocytoma; Glioblastoma; Genomic instability; p53
Genomic instability induced by mutant succinate dehydrogenase subunit D (SDHD) is mediated by O2-⢠and H2O2
Keywords: بی ثباتی ژنوم ; Succinate dehydrogenase mutations; Mutation frequency; Mutation rate; Genomic instability; Reactive oxygen species;
The complex basis underlying common fragile site instability in cancer
Keywords: بی ثباتی ژنوم ; fragile sites; replication; cancer; genomic instability; DNA damage; dormant origins
Pan-colonic field defects are detected by CGH in the colons of UC patients with dysplasia/cancer
Keywords: بی ثباتی ژنوم ; Ulcerative colitis; Genomic instability; BAC array
Potential G-quadruplex formation at breakpoint regions of chromosomal translocations in cancer may explain their fragility
Keywords: بی ثباتی ژنوم ; Genomic instability; Double-strand break; Altered DNA structures; DNA damage; Nonhomologous DNA end joining; Chromosomal translocation
Mechanisms of cadmium induced genomic instability
Keywords: بی ثباتی ژنوم ; Cadmium; Cancer; DNA repair; Epigenetic; Genotoxicity; Genomic instability
Quantitative proteomic analysis of mitochondrial proteins reveals prosurvival mechanisms in the perpetuation of radiation-induced genomic instability
Keywords: بی ثباتی ژنوم ; Mitochondria; Quantitative mass spectrometry; Proteomics; Genomic instability; Epigenetics; miR; Free radicals;
Changing paradigms in radiobiology
Keywords: بی ثباتی ژنوم ; Ionizing radiation; Nontargeted effects; Bystander effects; Genomic instability; Linear nonthreshold model; History of science
Utilization of fluorescence in situ hybridization with cytokeratin discriminators in TOP2A assessment of chemotherapy-treated patients with breast cancer
Keywords: بی ثباتی ژنوم ; Breast cancer; Personalized medicine; TOP2A; Anthracycline; Methotrexate; Biomarker; Genomic instability
Antimutagenic effect of Phellinus rimosus (Berk) Pilat against chemical induced mutations of histidine dependent Salmonella typhimurium strains
Keywords: بی ثباتی ژنوم ; Antimutagenicity; Mutagens; Genomic instability; Cancer chemoprevention; Macro fungus;
A comparison of two cell regulatory models entailing high dimensional attractors representing phenotype
Keywords: بی ثباتی ژنوم ; Phenotype represented by attractor; Cell regulation; Epigenetics; Speciation; Genomic instability; Somatic and hereditary disease;
Dynamics of Delayed p53 Mutations in Mice Given Whole-Body Irradiation at 8 Weeks
Keywords: بی ثباتی ژنوم ; Irradiation; Mouse; p53; Delayed mutation; Genomic instability;
A history of TFIIH: Two decades of molecular biology on a pivotal transcription/repair factor
Keywords: بی ثباتی ژنوم ; TFIIH; Helicase; DNA repair; Genomic instability
Glucose deprivation is associated with Chk1 degradation through the ubiquitin-proteasome pathway and effective checkpoint response to replication blocks
Keywords: بی ثباتی ژنوم ; Chk1; Glucose deprivation; Protein stability; Ubiquitin-proteasome pathway; Genomic instability;
Centrosomal dysregulation in human metastatic melanoma cell lines
Keywords: بی ثباتی ژنوم ; Centrosome; pericentrin; melanoma; genomic instability
p53: Guardian of ploidy
Keywords: بی ثباتی ژنوم ; Aneuploidy; Tetraploidy; p53; Lats2; Genomic instability; Oncogenic H-Ras;
Genomic instability and cancer: Lessons learned from human papillomaviruses
Keywords: بی ثباتی ژنوم ; Cancer; Genomic instability; Human papillomavirus; Centrosome; DNA damage;
Genomic characterization of Imatinib resistance in CD34+ cell populations from chronic myeloid leukaemia patients
Keywords: بی ثباتی ژنوم ; Chronic myeloid leukaemia; Imatinib resistance; Genomic instability; CGH array
Long-range massively parallel mate pair sequencing detects distinct mutations and similar patterns of structural mutability in two breast cancer cell lines
Keywords: بی ثباتی ژنوم ; Copy number variation; fosmid diTag; gene fusion; genomic instability; massively parallel sequencing
Why do we need a new paradigm in radiobiology?
Keywords: بی ثباتی ژنوم ; Genomic instability; Dynamic attractor; Evolution; Epigenetics; Radiation risk; New paradigm
The role of DNA repair in benzene-induced carcinogenesis
Keywords: بی ثباتی ژنوم ; Benzene; DNA repair; genomic instability
Some important questions connected with non-targeted effects
Keywords: بی ثباتی ژنوم ; Paradigm shift; Bystander effect; Genomic instability; Radiation biology
Transgenerational changes in somatic and germ line genetic integrity of first-generation offspring derived from the DNA damaged sperm
Keywords: بی ثباتی ژنوم ; Sperm DNA damage; preimplantation embryos; genomic instability; transgenerational effect
Genomic instability and rapid clinical course in adult T-cell lymphoma/leukemia patient
Keywords: بی ثباتی ژنوم ; Adult T-cell leukemia/lymphoma; Human T-cell leukemia virus type I; Genomic instability; Carcinogennesis;
Non-targeted effects as a paradigm breaking evidence
Keywords: بی ثباتی ژنوم ; Low-dose radiation effects; Bystander effect; Genomic instability; Low-dose hypersensitivity; Hormesis; Radioadaptive response; Transgenerational response
Increased DNA damage in hematopoietic cells of mice with graft-versus-host disease
Keywords: بی ثباتی ژنوم ; Micronucleus; Inflammation; Transplantation; Genomic instability; TNF-α; GVHD;
Role of Ku80-dependent end-joining in delayed genomic instability in mammalian cells surviving ionizing radiation
Keywords: بی ثباتی ژنوم ; Ionizing radiation; Genomic instability; DNA repair; Chromosome aberration; Non-homologous end-joining; CHO
Activation of mitogen-activated protein kinases cellular signal transduction pathway in mammalian cells induced by silicon carbide nanowires
Keywords: بی ثباتی ژنوم ; Mitogen-activated protein kinases; Cyclooxygenase-2; Phosphorylation; Apoptosis; Silicon carbide nanowires; Genomic instability
High-throughput SNP/CGH approaches for the analysis of genomic instability in colorectal cancer
Keywords: بی ثباتی ژنوم ; CRC, colorectal cancer; CRA, colorectal adenomaColorectal cancer; Genomic instability; Loss of heterozygosity; Single nucleotide polymorphisms; Comparative genomic hybridization
Arecoline arrests cells at prometaphase by deregulating mitotic spindle assembly and spindle assembly checkpoint: Implication for carcinogenesis
Keywords: بی ثباتی ژنوم ; Arecoline; Betel quid; Chromosomal aberrations; Genomic instability; Mitotic arrest; Spindle assembly checkpoint
Functions of base selection step in human DNA polymerase α
Keywords: بی ثباتی ژنوم ; Genomic instability; DNA polymerase; HNPCC; Mismatch repair; Mutation
A quantitative analysis of genomic instability in lymphoid and plasma cell neoplasms based on the PIG-A gene
Keywords: بی ثباتی ژنوم ; Genomic instability; Hypermutability; Lymphoid neoplasms; Plasma cell neoplasms; PIG-A gene; GPI-linked proteins
Transgenerational developmental effects and genomic instability after X-irradiation of preimplantation embryos: Studies on two mouse strains
Keywords: بی ثباتی ژنوم ; Embryos; Irradiation; Genomic instability; Transgenerational; Anomalies; Malformations
Graft-versus-Host Disease: Role of Inflammation in the Development of Chromosomal Abnormalities of Keratinocytes
Keywords: بی ثباتی ژنوم ; Squamous cell carcinoma; Inflammation; Keratinocytes; Genomic instability; Aneuploidy; Tetraploidy
Identification of genes associated with non-small-cell lung cancer promotion and progression
Keywords: بی ثباتی ژنوم ; Genomic instability; Non-small-cell lung cancer; Tumor progression; Tumor promotion
Molecular mechanisms of isocyanate induced oncogenic transformation in ovarian epithelial cells
Keywords: بی ثباتی ژنوم ; Reproductive Toxicity; Carcinogenesis; Methyl isocyanate; Senescence; DNA damage repair; Genomic instability
Nuclear imaging in three dimensions: A unique tool in cancer research
Keywords: بی ثباتی ژنوم ; 3D nuclear imaging; Telomeres; Chromosomes; Shelterin; Genomic instability; Nucleus; Cancer;