Keywords: متابولیسم کبدی; Insecticide; Hepatic metabolism; Energy metabolism; ATP metabolism;
مقالات ISI متابولیسم کبدی (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: متابولیسم کبدی; Lead; Gut microbiota; Hepatic metabolism; Zebrafish;
Keywords: متابولیسم کبدی; Microfluidics; Drug testing; Hepatic metabolism; Nephrotoxicity; Organs-on-a-chip;
Keywords: متابولیسم کبدی; Propamocarb; Hepatic metabolism; Gut microbiota; Microbial metabolites; Mice;
Keywords: متابولیسم کبدی; Herbacetin; Pharmacokinetics; Biotransformation; Glucuronidation; Hepatic metabolism; Colonic degradation;
Keywords: متابولیسم کبدی; Rhynchophylline (PubChem CID: 5281408); Isorhynchophylline (PubChem CID: 3037048); Diazepam (PubChem CID: 3016); Verapamil (PubChem CID: 2520); Rhynchophylline; Isorhynchophylline; Stereoselective pharmacokinetics; First-pass effect; Hepatic metabolism; B
Keywords: متابولیسم کبدی; Herbicides; Hepatic metabolism; Hepatic perfusion; Isolated mitochondria;
Keywords: متابولیسم کبدی; transporters; metabolism; drug-metabolizing enzymes; pharmacokinetics; hepatic transport; hepatic metabolism; organic anion-transporting polypeptide transporters; ALT; alanine aminotransferase; AST; aspartate aminotransferase; ATP; adenosine triphosphate;
Keywords: متابولیسم کبدی; physiologically based pharmacokinetic modeling; transporters; hepatobiliary disposition; hepatic metabolism; mathematical model; AUC; area under the concentration-time curve; Cmax; maximum plasma concentration; CYP; cytochrome P450 enzyme; CL; clearance;
Keywords: متابولیسم کبدی; physiologically based pharmacokinetic modeling; drug interactions; Monte Carlo; in vitro-in vivo correlations (IVIVC); nonlinear regression; biliary excretion; biliary recycling; hepatic metabolism; hepatic transport; AUC; area under the curve of concen
Keywords: متابولیسم کبدی; Chronic hypobaric hypoxia; CYP2C9; Hepatic metabolism; Ibuprofen; Pharmacokinetics
Keywords: متابولیسم کبدی; in vitro/in vivo correlations (IVIVC); hepatic clearance; hepatic metabolism; hepatic transport; transporters; drug transport; drug metabolizing enzymes; HIV/AIDS; FBS; fetal bovine serum; HEPES; 4-(2-hydroxyethyl)-1- piperazine ethanesulfonic acid; HIV
Keywords: متابولیسم کبدی; in vitro/in vivo correlations (IVIVC); hepatic transport; hepatic metabolism; hepatic clearance; hepatocytes; HIV/AIDS; membrane transport; metabolism; organic anion-transporting polypeptide transporters; APV; amprenavir; ATV; atazanavir; CHO; Chinese h
Keywords: متابولیسم کبدی; Caffeine; Semi-physiological model; Hepatic metabolism; Validation; Simulation
Keywords: متابولیسم کبدی; early lactation; hepatic metabolism; propionate; palmitate;
Keywords: متابولیسم کبدی; Polar bear; Ringed seal; Beluga whale; PFOS precursors; In vitro; Hepatic metabolism;
Keywords: متابولیسم کبدی; Model integration; Kinetic models; Logical networks; Insulin and glucagon signalling; Gene regulation; Hepatic metabolism
Keywords: متابولیسم کبدی; Hepatic metabolism; Liver perfusion; Uncoupling; Toxicology;
Short-chain chlorinated paraffins (SCCPs) induced thyroid disruption by enhancement of hepatic thyroid hormone influx and degradation in male Sprague Dawley rats
Keywords: متابولیسم کبدی; Short-chain chlorinated paraffins; Thyroid disruption; Hepatic metabolism; Thyroid hormone; Constitutive androstane receptor;
High-fat diet alters PAS kinase regulation by fasting and feeding in liver
Keywords: متابولیسم کبدی; ACC; acetyl CoA carboxylase; Akt/PKB; protein kinase B; CHREBP; carbohydrate-responsive element-binding protein; CPT1-A; carnitine palmitoyltransferase 1A; DAPI; 4,6-diamidino-2-phenylindole; FAS; fatty acid synthase; FOXO1; forkhead box protein O1; GCK;
Comparative proteomic analysis of hepatic mechanisms of Megalobrama amblycephala infected by Aeromonas hydrophila
Keywords: متابولیسم کبدی; Aeromonas hydrophila; Proteome; Immunity; Hepatic metabolism; Megalobrama amblycephala;
Hepatic microsomal metabolism of BDE-47 and BDE-99 by lesser snow geese and Japanese quail
Keywords: متابولیسم کبدی; BDE-47; BDE-99; Lesser snow goose; Japanese quail; Hepatic metabolism; UHPLC/MS/MS;
Current In Vitro Methods to Determine Hepatic Kpuu: A Comparison of Their Usefulness and Limitations
Keywords: متابولیسم کبدی; active transport; passive diffusion/transport; hepatic metabolism; biliary excretion; distribution; disposition; tissue partition; protein binding; hepatocytes; human liver microsomes; ABT; 1-aminobenzotriazole; AFE; average fold error; CLint; intrinsic c
Calcium effects and systemic exposure of vitamin D3 analogues after topical treatment of active vitamin D3-containing ointments in rats
Keywords: متابولیسم کبدی; Vitamin D3-containing ointment; Systemic exposure; Skin permeation; Hepatic metabolism; Calcemic effect;
Interspecies Differences in the Metabolism of a Multiester Prodrug by Carboxylesterases
Keywords: متابولیسم کبدی; enzymes; hepatic metabolism; HPLC (high-performance/pressure liquid chromatography); intestinal metabolism; metabolism; prodrugs;
Ketoconazole Stereoisomers Differentially Induce Cytochrome P450 1A1 Between Human Hepatoma HepG2 and Mouse Hepatoma Hepa1c1c7 Cells
Keywords: متابولیسم کبدی; cytochrome P450; dose-response; drug metabolizing enzymes; enzyme kinetics; enzymes; hepatic clearance; hepatic metabolism; kinetics;
Primaquine pharmacology in the context of CYP 2D6 pharmacogenomics: Current state of the art
Keywords: متابولیسم کبدی; ADH; Aldehyde dehydrogenase; CYP; Cytochrome P450; G6PD; Glucose-6-phosphate dehydrogenase; IVIS; In vivo imaging system; MOA; Monoamine oxidase; ROS; Reactive oxygen species; Primaquine; CYP 2D6; 8-Aminoquinoline; Pharmacogenomics; Hepatic metabolism; Pl
Carbon Monoxide-Bound Red Blood Cell Resuscitation Ameliorates Hepatic Injury Induced by Massive Hemorrhage and Red Blood Cell Resuscitation via Hepatic Cytochrome P450 Protection in Hemorrhagic Shock Rats
Keywords: متابولیسم کبدی; cytochrome P450; pharmacokinetics; drug transport; hepatic metabolism; drug effects; RBC, red blood cells; CO, carbon monoxide; CORMs, CO-releasing molecules; CO-RBC, carbon monoxide-bound red blood cell; CYP, cytochrome P450; AST, aspartate aminotransfer
Complex metabolic interactions between benzo(a)pyrene and tributyltin in presence of dichlorodiphenyltrichloroethane in South American catfish Rhamdia quelen
Keywords: متابولیسم کبدی; BaP; Tributyltin; DDT; Hepatic metabolism; Bile; Fish;
Effects of nuclear receptor transactivation on boar taint metabolism and gene expression in porcine hepatocytes
Keywords: متابولیسم کبدی; Androstenone; Skatole; Hepatic metabolism; Cytochrome P450;
Dysregulation of Npas2 leads to altered metabolic pathways in a murine knockout model
Keywords: متابولیسم کبدی; Circadian metabolism; Circadian gene regulation; Fetal circadian responses; Hepatic metabolism;
Hepatic metabolism of ibuprofen in rats under acute hypobaric hypoxia
Keywords: متابولیسم کبدی; Acute hypobaric hypoxia; Hepatic metabolism; Pharmacokinetics; Ibuprofen; CYP2C9 level
Disposition of ON 01210.Na (Ex-RAD(R)), a Novel Radioprotectant, in the Isolated Perfused Rat Liver: Probing Metabolic Inhibition to Increase Systemic Exposure
Keywords: متابولیسم کبدی; metabolic clearance; disposition; drug interactions; hepatic metabolism; glutathione-S-transferases; preclinical pharmacokinetics;
Metabolic Characterization of Primary Rat Hepatocytes Cultivated in Parallel Microfluidic Biochips
Keywords: متابولیسم کبدی; hepatocytes; hepatic metabolism; drug delivery system; cytochrome P450; phase II metabolism; efflux pumps; in vitro models
Metabolism of a Serotonin-4 Receptor Partial Agonist 4-{4-[4-Tetrahydrofuran-3-yloxy)-Benzo[d]Isoxazol-3-yloxymethyl]-Piperidin-1-ylmethyl}-Tetrahydropyran-4-ol (TBPT): Identification of an Unusual Pharmacologically Active Cyclized Oxazolidine Metabolite
Keywords: متابولیسم کبدی; metabolism; microsomes; protein binding; mass spectrometry; hepatic metabolism
Oncology/EndocrineImpact of hepatic malignancy on CYP3A4 gene expression
Keywords: متابولیسم کبدی; Liver; Malignancy; Hepatic metabolism; CYP3A4;
Hepatic expression of cytochrome P450 in type 2 diabetic Goto–Kakizaki rats
Keywords: متابولیسم کبدی; Diabetes; GK rat; Cytochrome P450; Hepatic metabolism; Ketone body
Pathophysiologic role of hepatocyte nuclear factor 6
Keywords: متابولیسم کبدی; HNF6; Liver injury; Cell cycle; Apoptosis; Cell proliferation; Hepatic metabolism; Hepatic fibrosis; Signal transduction;
Protective effects of calcium on copper toxicity in Pelteobagrus fulvidraco: Copper accumulation, enzymatic activities, histology
Keywords: متابولیسم کبدی; Pelteobagrus fulvidraco; Copper toxicity; Calcium; Hepatic metabolism; Histology; Copper accumulation
A comprehensive evaluation of metabolic activity and intrinsic clearance in suspensions and monolayer cultures of cryopreserved primary human hepatocytes
Keywords: متابولیسم کبدی; hepatic clearance; hepatic metabolism; hepatocytes; metabolic clearance; CYP enzymes; cytochrome P450; clearance; flavin monooxygenases (FMO);
Use of Physiologically Based Pharmacokinetic Models to Evaluate the Impact of Intestinal Glucuronide Hydrolysis on the Pharmacokinetics of Aglycone
Keywords: متابولیسم کبدی; Intestinal metabolism; hepatic metabolism; UGTs; glucuronidation; intestinal bacteria; ABC transporters; pharmacokinetics;
Poloxamer 407 Increases the Recovery of Paracetamol in the Isolated Perfused Rat Liver
Keywords: متابولیسم کبدی; disposition; elimination; endothelial; protein binding; surfactants; pharmacokinetics/pharmacodynamics; hepatocytes; hepatic metabolism; hepatic clearance; disposition
Hepatic response to aluminum toxicity: Dyslipidemia and liver diseases
Keywords: متابولیسم کبدی; Aluminum toxicity; Hepatic metabolism; Dyslipidemia; Obesity; Liver diseases
An examination of the potential effect of lipids on the firstâpass metabolism of the lipophilic drug anethol trithione
Keywords: متابولیسم کبدی; anethol trithione; medium chain triglycerides; firstâpass metabolism; hepatic metabolism; nonlinear pharmacokinetics; dose proportionality; drug metabolizing enzymes; inhibition; formulation; lipids;
In vitro metabolism and disposition of honokiol in rat and human livers
Keywords: متابولیسم کبدی; honokiol; hepatic metabolism; hepatic clearance; biliary excretion; glucuronidation; sulfation;
Simultaneous Absolute Quantification of 11 Cytochrome P450 Isoforms in Human Liver Microsomes by Liquid Chromatography Tandem Mass Spectrometry with In Silico Target Peptide Selection
Keywords: متابولیسم کبدی; CYP enzymes; cytochrome P450; hepatic metabolism; LC-MS/MS; mass spectrometry; metabolism; microsomes; proteomics; quantification
Effects of Normothermic Hepatic Ischemia-Reperfusion Injury on the In Vivo, Isolated Perfused Liver, and Microsomal Disposition of Chlorzoxazone, a Cytochrome P450 2E1 Probe, in Rats
Keywords: متابولیسم کبدی; hepatic ischemia-reperfusion injury; pharmacokinetics; isolated perfused rat liver; hepatobiliary disposition; microsomes; cytochrome P450 2E1; cytochrome P450 reductase; chlorzoxazone; hepatic metabolism; metabolite kinetics;
Genetic variations of orosomucoid genes associated with serum alphaâ1âacid glycoprotein level and the pharmacokinetics of paclitaxel in Japanese cancer
Keywords: متابولیسم کبدی; alphaâ1âacid glycoprotein; ORM1; ORM2; paclitaxel; pharmacogenomics; pharmacokinetics; glycoproteins/glycoprotein receptors; hepatic metabolism; cancer chemotherapy;
Using erlotinib to treat patients with non-small cell lung cancer who continue to smoke
Keywords: متابولیسم کبدی; Erlotinib; Smoking; Pharmacology; Hepatic metabolism; Biomarkers
Effect of waterborne copper exposure on growth, hepatic enzymatic activities and histology in Synechogobius hasta
Keywords: متابولیسم کبدی; Copper toxicity; Synechogobius hasta; Histology of gill and liver; Hepatic metabolism; Fatty liver syndrome