β-Thujaplicinol inhibits hepatitis B virus replication by blocking the viral ribonuclease H activity
Keywords: ویروس نقص ایمنی انسانی; HBV, hepatitis B virus; cccDNA, covalently-closed circular DNA; RC DNA, relaxed circular DNA; RNAseH, ribonuclease H; HIV, human immunodeficiency virus; βTJ, β-thujaplicinol; HRHPL, recombinant wild-type HBV RNAseH; HRHPL-D702A, active site mutant of reco