Keywords: گلوله گلوله; Protein misfolding; High-pressure spectroscopy; Molten globule; Urea; High hydrostatic pressure; Alpha-synuclein; p53;
مقالات ISI گلوله گلوله (ترجمه نشده)
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Keywords: گلوله گلوله; Aggregates; Partially folded state; Hydrophobic clusters; Molten globule; Secondary structure; Glyoxal; Trifluoroethanol;
Keywords: گلوله گلوله; 5-Aminolevulinate synthase; Pyridoxal phosphate; Heme; Molten globule; Protein unfolding; ALAS; 5-aminolevulinate synthase; mALAS2; murine erythroid-specific 5-aminolevulinate synthase; PLP; pyridoxal 5â²-phosphate; ANS; 8-anilino-1-naphtalenesulfonic ac
Keywords: گلوله گلوله; BCA II; bovine carbonic anhydrase II; PMG; pre molten globule; MG; molten globule; ThT; thioflavin T; CD; circular dichroism; AFM; atomic force microscopy; ANS; 1-anilino-naphthalene 8-sulfonate; DLS; dynamic light scattering; TFE; 2,2,2-trifluoroethanol;
Keywords: گلوله گلوله; Kinesin; Molten globule; Conformational selection; Induced fit; Osmolyte effect;
Keywords: گلوله گلوله; Molten globule; Folding; Dynamic light scattering
Keywords: گلوله گلوله; BoNT, botulinum neurotoxin; BoNT/A LC, botulinum neurotoxin light chain (LCA); LED, light emitting diode; DTT, dithiothreitol; CD, circular dichroism; RCT, rotational correlation timeFluorescence anisotropy decay; Molten globule; Protein flexibility; Botu
Keywords: گلوله گلوله; Computational design; Directed evolution; Intrinsically disordered proteins; Molten globule; Protein–protein interactions; Protein–receptor interface; Yeast surface display
Keywords: گلوله گلوله; α-LA; α-lactalbumin; apo-α-LA; Ca2 +-depleted α-LA; BLA; bovine α-LA; CD; circular dichroism; DLS; dynamic light scattering; EDTA; ethylenediaminetetraacetic acid; ELOA; OA-complex of equine lysozyme; FTIR; Fourier-transform infrared spectroscopy; G
Keywords: گلوله گلوله; HSQC; heteronuclear single-quantum coherences; MD; molecular dynamics; DSS; 2,2-dimethyl-2-silapentane-5-sulfonic acid; TSP; 3-(trimethylsilyl) propionate sodium salt; MG; molten globule; GB1; protein G; High pressure NMR; Pressure-induced chemical shifts
Keywords: گلوله گلوله; Protein kinase A; Acrylodan label; Fluorescence assay; Protein unfolding; Intermediate; molten globule
Stabilizing vitamin D3 using the molten globule state of α-lactalbumin
Keywords: گلوله گلوله; α-lactalbumin; molten globule; vitamin D; stability; fortification;
Disorder-to-order transitions in the molten globule-like Golgi Reassembly and Stacking Protein
Keywords: گلوله گلوله; Golgi Reassembly and Stacking Protein; Intrinsically disordered proteins; Molten globule; Disorder-to-order transition; Spectroscopy;
Study of a novel agent for TCA precipitated proteins washing - comprehensive insights into the role of ethanol/HCl on molten globule state by multi-spectroscopic analyses
Keywords: گلوله گلوله; Protein precipitation; Trichloroacetic acid; Molten globule; Solubilization; Spectroscopy; Mechanistic;
Unraveling the differential structural stability and dynamics features of T7 endolysin partially folded conformations
Keywords: گلوله گلوله; Bacteriophage; T7 endolysin; Amidase; Lysozyme; Partially folded conformation; Molten globule;
Macromolecular crowding induces molten globule state in the native myoglobin at physiological pH
Keywords: گلوله گلوله; Crowding agent; Docking studies of myoglobin; Molten globule; Fluorescence spectroscopy; Circular dichroism; Isothermal titration calorimetry;
Effect of conservative mutations (L94V and L94I) on the structure and stability of horse cytochrome c
Keywords: گلوله گلوله; Horse cytochrome c; Molten globule; Protein stability; Protein denaturation; Site-directed mutagenesis;
Investigating the folding pathway and substrate induced conformational changes in B. malayi Guanylate kinase
Keywords: گلوله گلوله; NMP kinase; nucleoside monophosphate kinase; BmGK; Brugia malayi Guanylate kinase; SEC; Size Exclusion chromatography; GdnCl; guanidine hydrochloride; MS; molecular simulation; B. malayi Guanylate Kinase; Unfolding; Molten globule;
pH induced single step shift of hydrophobic patches followed by formation of an MG state and an amyloidogenic intermediate in Lima Bean Trypsin Inhibitor (LBTI)
Keywords: گلوله گلوله; LBTI; Lima Bean Trypsin Inhibitor; MG; molten globule; PPI; protein protease inhibitor; PI; protease inhibitor; Ia; amyloidiogenic intermediate; Y69; tyrosine 69; E70; glutamate 70; GdnHCl; guanidine hydrochloride; TEM; transmission electron microscopy; C
Structural and thermodynamic characterisation of L94F mutant of horse cytochrome c
Keywords: گلوله گلوله; Horse cytochrome c; Molten globule; Pre-molten globule; Thermodynamic stability; Protein denaturation; MD simulation;
Ribosomal Protein P2 from apicomplexan parasite Toxoplasma gondii is intrinsically a molten globule
Keywords: گلوله گلوله; Apicomplexa; Toxoplasma gondii P2 (TgP2); Molten globule; NMR;
Molten globule nature of Plasmodium falciparum P2 homo-tetramer
Keywords: گلوله گلوله; NMR; Plasmodium falciparum P2 (PfP2); PfP2 structure; Molten globule; Folding and dynamics
Role of macromolecular crowding and salt ions on the structural-fluctuation of a highly compact configuration of carbonmonoxycytochrome c
Keywords: گلوله گلوله; Molten globule; Macromolecular crowding effect; Structural-fluctuation; Van der Waals bumps; Excluded volume effect; Enthalpic and entropic effects;
Thermal induced unfolding of human serum albumin isomers: Assigning residual α helices to domain II
Keywords: گلوله گلوله; Human serum albumin; Denaturation; Molten globule; Urea;
Conformational transitions of cinnamoyl CoA reductase 1 from Leucaena leucocephala
Keywords: گلوله گلوله; Conformation; Unfolding; Molten globule; Thermostability; Aggregation; Cinnamoyl CoA reductase
Catalytically active alkaline molten globular enzyme: Effect of pH and temperature on the structural integrity of 5-aminolevulinate synthase
Keywords: گلوله گلوله; Aminolevulinate synthase; Pyridoxal-5â²phosphate; Heme; Molten globule; Protein folding; Intrinsically disordered proteins;
FlgM proteins from different bacteria exhibit different structural characteristics
Keywords: گلوله گلوله; FlgM; Intrinsically disordered protein; Circular dichroism; Molten globule
Polypeptide chain collapse and protein folding
Keywords: گلوله گلوله; Unfolded state dynamics; Polypeptide chain collapse; Molten globule; Folding mechanisms; Hydrophobic collapse
Halogenol- versus alkanol-induced structural transitions of acid-denatured glucoamylase: Characterization of alcohol-induced states
Keywords: گلوله گلوله; ANS, 1-anilinonaphthalene-8-sulfonic acid; CD, circular dichroism; HFIP, 1,1,1,3,3,3-hexafluoro-2-propanol; MRE, mean residue ellipticity; TFE, 2,2,2-trifluoroethanol; Trp, tryptophan; Tyr, tyrosineGlucoamylase; Molten globule; Acid-denatured state; Alcoh
Molecular dynamics simulation of the effect of heat on the conformation of bovine β-lactoglobulin A: A comparison of conventional and accelerated methods
Keywords: گلوله گلوله; β-Lactoglobulin; Denaturation; Molecular dynamics simulation; Essential dynamics; Replica exchange molecular dynamics; Molten globule
Polyol osmolytes stabilize native-like cooperative intermediate state of yeast hexokinase A at low pH
Keywords: گلوله گلوله; Molten globule; Osmolytes; Polyols; Cooperative structure; Thermal stability; Yeast hexokinase A; Calorimetry; DSC; differential scanning calorimetry; MG; molten globule; CD; circular dichroism; ANS; 8-anilino-1-naphthalene sulfonic acid;
Differential domain structure stability of the severe acute respiratory syndrome coronavirus papain-like protease
Keywords: گلوله گلوله; Viral protease; Deubiquitination; Reversible three-state unfolding; Molten globule; Analytical ultracentrifugation;
Importance of polypeptide chain length for the correct local folding of a β-sheet protein
Keywords: گلوله گلوله; α â β Transition; β-Hairpin; Circular dichroism; Non-native α-helix; 8-Anilino-1-napthalenesulfonic acid; Molten globule;
Differing structural characteristics of molten globule intermediate of peanut lectin in urea and guanidine-HCl
Keywords: گلوله گلوله; PNA; peanut agglutinin; ANS; 8-anilino-1-naphthalenesulfonate; NBS; N-bromosuccinimide; GdnHCl; guanidine hydrochloride; PBS; 20Â mM sodium phosphate buffered with 0.15Â M NaCl, pH 7.2; CD; circular dichroism; HPLC; high performance liquid chromatography;
Acidic pH promotes oligomerization and membrane insertion of the BclXL apoptotic repressor
Keywords: گلوله گلوله; Protein oligomerization; Molten globule; Membrane insertion; Ligand binding; Allosteric regulation;
The cross-road between the mechanisms of protein folding and aggregation; study of human stefin B and its H75W mutant
Keywords: گلوله گلوله; Amyloid fibril formation; Kinetics of protein folding; Folding intermediate; Molten globule; ANS fluorescence; Cystatins stefin B;
Dioxane enhanced immobilization of urease on alkyl modified nano-porous silica using reversible denaturation approach
Keywords: گلوله گلوله; Urease; Immobilization; Porous silica; Dioxane; Molten globule; Intermediate; Unfolding
Trifluoroethanol stabilizes the molten globule state and induces non-amyloidic turbidity in stem bromelain near its isoelectric point
Keywords: گلوله گلوله; ANS; 1-anilino-8-naphthalene sulfonic acid; CD; circular dichroism; GdnHCl; guanidine hydrochloride; MG; molten globule; NATA; N-acetyl-l-tryptophanamide; SBM; stem bromelain; SMG; specific molten globule; TFE; 2,2,2-trifluoroethanol; ThT; thioflavin T; A
Acetonitrile can promote formation of different structural intermediate states on aggregation pathway of immunoglobulin G from human and bovine
Keywords: گلوله گلوله; Acetonitrile; Hydrophobic residues; Molten globule; Secondary structure; Thioflavin T;
Thermal unfolding of apo- and holo-enolase from Saccharomyces cerevisiae: Different mechanisms, similar activation enthalpies
Keywords: گلوله گلوله; CD; circular dichroism; tris; tris(hydroxy-methyl) aminomethane; Gdn-HCl; guanidine hydrochloride; PGA; 2-phosphoglycerate; PEP; phosphoenolpyruvate; Thermal unfolding kinetics; Intermediate state; Monomer; Dimer; Circular dichroism; Irreversibility; Molt
Structural characterization and unfolding mechanism of human 4F2hc ectodomain
Keywords: گلوله گلوله; CD98hc; Circular dichroism; Fluorescence spectroscopy; Molten globule; TIM barrel; Urea denaturation.;
Biophysical analysis of partially folded state of α-lactalbumin in the presence of cationic and anionic surfactants
Keywords: گلوله گلوله; α-LA; Molten globule; Electrostatic interaction; Hydrophobic interaction; ζ-Potential; Hydrodynamic diameter
Spectroscopic study on acid-induced unfolding and refolding of apo-neuroglobin
Keywords: گلوله گلوله; Neuroglobin; Apo-Neuroglobin; Acid denaturation; Unfolding; Molten globule;
Organization and dynamics of tryptophans in the molten globule state of bovine α-lactalbumin utilizing wavelength-selective fluorescence approach: Comparisons with native and denatured states
Keywords: گلوله گلوله; Molten globule; α-Lactalbumin; Red edge excitation shift; Protein conformation; Fluorescence anisotropy; Fluorescence lifetimeBLA, bovine α-lactalbumin; FRET, fluorescence resonance energy transfer; REES, red edge excitation shift
Specific molten globule conformation of stem bromelain at alkaline pH
Keywords: گلوله گلوله; Protein folding; Alkaline denaturation; Bromelain; Molten globule; Temperature endotherm; Thermodynamics
Multistate unfolding of α-mannosidase from Canavalia ensiformis (Jack Bean): Evidence for the thermostable molten globule
Keywords: گلوله گلوله; α-Mannosidase; Molten globule; Fluorescence; Circular dichroism; Guanidine hydrochloride; Unfolding; Thermostability
More stable structure of wheat germ lipase at low pH than its native state
Keywords: گلوله گلوله; Acid-induced state; Enzyme activity; Molten globule; pH-induced denaturation; Wheat germ lipase
Reduced stability and enhanced surface hydrophobicity drive the binding of apo-aconitase with GroEL during chaperone assisted refolding
Keywords: گلوله گلوله; ANS; 1-anilino naphthalene-8-sulfonate; GdnHCl; guanidine hydrochloride; MG; molten globule; N; native; U; unfolded; PK; proteinase K; Apo-aconitase; Holo-aconitase; Aconitase unfolding; GroEL-assisted folding; Metallo protein biosynthesis;
Temperature-induced unfolding of epidermal growth factor (EGF): Insight from molecular dynamics simulation
Keywords: گلوله گلوله; Human epidermal growth factor (EGF); Thermal denaturation; Replica exchange molecular dynamics simulations; Free-energy landscape; Molten globule; Transition state; Unfolding kinetics
Investigation of the unfolding pathway of Bacillus thuringiensis Cyt2Aa2 toxin reveals an unfolding intermediate
Keywords: گلوله گلوله; Cyt2Aa2; Bacillus thuringiensis; Protein unfolding; Molten globule; Intrinsic fluorescence; Circular dichroism