دانلود مقالات ISI درباره MT، میکروتوبول + ترجمه فارسی

Chemical synthesis, pharmacological evaluation and in silico analysis of new 2,3,3a,4,5,6-hexahydrocyclopenta[c]pyrazole derivatives as potential anti-mitotic agents

Keywords: MT، میکروتوبول; EDG, electron donating group; EWG, electron withdrawing groups; MT, microtubule; SAR, structure activity relationshipHexahydropyrazole; Anti-mitotic; Tubulin; Docking; Tubulin binding assay; Colchicine-binding assay

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Bisphenol A disrupts microtubules and induces multipolar spindles in dividing root tip cells of the gymnosperm Abies cephalonica

Keywords: MT، میکروتوبول; Abies cephalonica; Bisphenol A; Multipolar spindle; Microtubules; Mitosis; Centrosomal propertiesBPA, bisphenol A; ER, endoplasmic reticulum; CLSM, confocal laser scanning microscopy; PPB, preprophase band; MT, microtubule

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Fidgetin-Like 2: A Microtubule-Based Regulator of Wound Healing

Keywords: MT، میکروتوبول; FA, focal adhesion complex; FL2, fidgetin-like 2; GFP, green fluorescent protein; MT, microtubule; NPsi, nanoparticle siRNA; siRNA, small interfering RNA

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

CLASP2 Has Two Distinct TOG Domains That Contribute Differently to Microtubule Dynamics

Keywords: MT، میکروتوبول; MT, microtubule; GSK3, glycogen synthase kinase 3; GFP, green fluorescent protein; EM, electron microscopy; ITC, isothermal titration calorimetrycrystal structure; microtubule; microtubule-associated protein (MAP); + TIPs; molecular modeling

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Neuronal stathmins: A family of phosphoproteins cooperating for neuronal development, plasticity and regeneration

Keywords: MT، میکروتوبول; CNS, central nervous system; DG, dentate gyrus; LTP, long-term potentiation; MT, microtubule; PAT, palmitoyl acetyl transferase; PC, Purkinje cell; PRD, proline-rich domain; SLD, stathmin-like domain; SLDN, N-terminal regions of SLD; TBR, tubulin-binding

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

PIVL, a snake venom Kunitz-type serine protease inhibitor, inhibits in vitro and in vivo angiogenesis

Keywords: MT، میکروتوبول; bFGF, basic fibroblast growth factor; CAM, chorioallantoic membrane; ECM, extracellular matrix; MT, microtubule; PIVL, protease inhibitor from Macrovipera lebetina; VEGF, vascular endothelial growth factorAngiogenesis; Chorioallantoic membrane assay; Inte

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Microtubule-targeting agents are clinically successful due to both mitotic and interphase impairment of microtubule function

Keywords: MT، میکروتوبول; MT, microtubule; MSA, microtubule-stabilizing agent; MDA, microtubule-destabilizing agent; MTA, microtubule-targeting agent; HIF-1α, hypoxia inducible factor 1α; PTX, paclitaxel Taxol®; VDA, vascular disrupting agent; BBB, blood brain barrierMicrotubule-t

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Early-onset cognitive deficits and axonal transport dysfunction in P301S mutant tau transgenic mice

Keywords: MT، میکروتوبول; NFTs, neurofibrillary tangles; FTLD, frontotemporal lobar degeneration; MT, microtubule; WT, wild type; Tg, transgenic; SEM, standard error of the meanTau; Axonal transport; Tg mouse model; Neurofibrillary tangles; Frontotemporal lobar degeneration; Alzhe

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Hyperthermia induces cytoskeletal alterations and mitotic catastrophe in p53-deficient H1299 lung cancer cells

Keywords: MT، میکروتوبول; MT, microtubule; MF, microfilament; IF, intermediate filamentHyperthermia; H1299 cells; Cytoskeleton; Cell death; Mitotic catastrophe

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Microtubule-binding sites of the CH domain of EB1 and its autoinhibition revealed by NMR

Keywords: MT، میکروتوبول; HSQC, heteronuclear single quantum correlation spectroscopy; TROSY, Transverse relaxation optimized spectroscopy; CSP, chemical shift perturbation; TCS, transferred cross-saturation; + TIPs, plus-end tracking proteins; MT, microtubule; EB1, end-binding pr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Synthesis of 5,7-disubstituted-4-methyl-7H-pyrrolo[2,3-d]pyrimidin-2-amines as microtubule inhibitors

Keywords: MT، میکروتوبول; MT, microtubule; MDR, multiple drug resistance; Pgp, P-glycoprotein; MRP, multidrug-resistance proteins; TLC, thin layer chromatography; NMR, nuclear magnetic resonance; HRMS, high resolution mass spectraPyrrolo[2,3-d]pyrimidines; Microtubule inhibitors;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Microtubule-associated protein tau in bovine retinal photoreceptor rod outer segments: Comparison with brain tau

Keywords: MT، میکروتوبول; AP, alkaline phosphatase; AD, Alzheimer's disease; BSA, bovine serum albumin; Cdk5, cyclin-dependent protein kinase 5; DTT, dithiothreitol; FTDP-17, front-temporal dementia with parkinsonism liked to chromosome; MT, microtubule; MW, molecular weight; PHF,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

NAP (davunetide) modifies disease progression in a mouse model of severe neurodegeneration: Protection against impairments in axonal transport

Keywords: MT، میکروتوبول; ALS, amyotrophic lateral sclerosis; SOD1, superoxide dismutase 1; SOD1-G93A, mutated SOD1; Tg, transgenic; MT, microtubule; VTA, ventral tegmental area; FTD, frontotemporal dementia; ADNP, activity dependent neuroprotective protein; FDR, false discovery r

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

Kinesin-5: Cross-bridging mechanism to targeted clinical therapy

Keywords: MT، میکروتوبول; KSP, kinesin spindle protein; ATP, adenosine-5′-triphosphate; KHC, kinesin heavy chain; kDa, kilodalton; MT, microtubule; STC, S-trityl-l-cysteine; CDK1, cyclin-dependent kinase 1; RNAi, ribonucleic acid interference; AP1, activator protein 1; siRNA, smal

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of differentially expressed genes in a spontaneous altered leaf shape mutant of the navel orange [Citrus sinensis (L.) Osbeck]

Keywords: MT، میکروتوبول; Citrus; Bud mutation; Leaf shape; Suppression subtractive hybridization; Expressed sequence tagSSH, suppression subtractive hybridization; ESTs, expressed sequence tags; MT, microtubule; WOX, WUSCHEL-like homeobox

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

VDAC inhibition by tubulin and its physiological implications

Keywords: MT، میکروتوبول; CTT, C-terminal tail; GSK3β, glycogen synthase kinase-3β; MOM, mitochondrial outer membrane; MT, microtubule; OxPhos, oxidative phosphorylation; PKA, cyclic AMP-dependent protein kinase A; VDAC, voltage-dependent anion channelVoltage-dependent anion chann

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Linkage of N-cadherin to multiple cytoskeletal elements revealed by a proteomic approach in hippocampal neurons

Keywords: MT، میکروتوبول; AMPA, 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid; CNS, central nervous system; HBSS, Hanks’ balanced salt solution; LC–MS/MS, liquid chromatography–tandem mass spectrometry; MAP kinase, mitogen-activated protein kinase; MT, microtubule; NMDA

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Hsp90 binds microtubules and is involved in the reorganization of the microtubular network in angiosperms

Keywords: MT، میکروتوبول; EPC, ethyl-N-phenylcarbamate; GDA, geldanamycin; MAP, microtubule-associated protein; MT, microtubule; PPB, preprophase bandCold; Heat-shock protein 90; Microtubules; Tobacco; Tubulin

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Parkin Co-Regulated Gene is involved in aggresome formation and autophagy in response to proteasomal impairment

Keywords: MT، میکروتوبول; 3-MA, 3-methyladenine; AV, autophagic vesicle; BSA, bovine serum albumin; ER, endoplasmic reticulum; FBS, foetal bovine serum; LB, Lewy body; LC3, light chain 3; MT, microtubule; MTOC, microtubule organising centre; PACRG, Parkin Co-Regulated Gene; PD, Pa

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

ORP10, a cholesterol binding protein associated with microtubules, regulates apolipoprotein B-100 secretion

Keywords: MT، میکروتوبول; apoB-100, apolipoprotein B-100; EGFP, enhanced green fluorescent protein; ER, endoplasmic reticulum; GST, glutathione-S-transferase; LDLR, low-density lipoprotein receptor; MT, microtubule; OHC, hydroxycholesterol; ORD, OSBP-related domain; ORP, OSBP-rela

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

The flavonoid eupatorin inactivates the mitotic checkpoint leading to polyploidy and apoptosis

Keywords: MT، میکروتوبول; SAC, the spindle assembly checkpoint; M phase, mitotic phase; 3D cell culture, 3-dimensional cell culture; APC/C, anaphase-promoting complex/cyclosome; MT, microtubule; MAPK, mitogen-activated protein kinase; HTS, high-throughput screen; FACS, fluorescent

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Effect of pharmaceutical agent degradation on axonal transport drug delivery: An analytical solution for a transient situation

Keywords: MT، میکروتوبول; MT, microtubule; PAC, pharmaceutical agent complexTargeted drug delivery; Neurons; Molecular motors; Axonal transport; Analytical solution

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Cytokeratin 18-mediated disorganization of intermediate filaments is induced by degradation of plectin in human liver cells

Keywords: MT، میکروتوبول; MT, microtubule; MF, microfilament; IF, intermediate filament; CK, cytokeratin; IFAP, intermediate filament associated protein; HCC, hepatocellular carcinoma; HRP, horseradish peroxidase; DMEM, Dulbecco’s minimum essential medium; FBS, fetal bovine serum;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

C-sequence of the Dictyostelium cytoplasmic dynein participates in processivity modulation

Keywords: MT، میکروتوبول; MT, microtubule; TIRF, total internal reflection fluorescence; GST, glutathione S-transferaseProcessivity; Cytoplasmic dynein; AAA+ ATPase; Dictyostelium

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Regulation of axonal mitochondrial transport and its impact on synaptic transmission

Keywords: MT، میکروتوبول; SNPH, syntaphilin; MT, microtubule; KIFs, kinesin superfamily proteins; KHC, kinesin heavy chains; KLC, kinesin light chains; DHC, dynein heavy chains; DIC, dynein intermediate chains; DLIC, dynein light intermediate chains; DLC, dynein light chains; dMir

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

The characterization of microtubule-stabilizing drugs as possible therapeutic agents for Alzheimer's disease and related tauopathies

Keywords: MT، میکروتوبول; AD, Alzheimer's disease; BBB, blood–brain barrier; B/P, brain-to-plasma; CNS, central nervous system; FTDP-17, frontotemporal dementia with Parkinsonism linked to chromosome 17; MDCK-MDR, Madin–Darby canine kidney cells expressing MDR1; MT, microtubule; N

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

plusTipTracker: Quantitative image analysis software for the measurement of microtubule dynamics

Keywords: MT، میکروتوبول; EB3, end-binding protein 3; LAP, linear assignment problem; MT, microtubule; +TIP, MT plus end binding protein; ROI, region of interestMicrotubule; Dynamics; Tracking; Live-cell; EB1; EB3

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Focal Adhesion Proteins Talin-1 and Vinculin Negatively Affect Paxillin Phosphorylation and Limit Retroviral Infection

Keywords: MT، میکروتوبول; retrovirus; HIV-1; cytoskeleton; focal adhesions; early blockHIV-1, human immunodeficiency virus type 1; M-MuLV, Moloney murine leukemia virus; SIV, simian immunodeficiency virus; VSV-G, vesicular stomatitis virus; MT, microtubule; FAK, focal adhesion kin

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2011 سفارش ترجمه

Cytoskeletal and developmental alterations in Ceratophyllum demersum induced by microcystin-LR, a cyanobacterial toxin

Keywords: MT، میکروتوبول; CMT, cortical microtubule; MCY-LR, microcystin-LR; MT, microtubule; PPB, preprophase bandCeratophyllum demersum; Microcystin-LR; Growth inhibition; Cell elongation; Microtubule reorientation; Shoot tip development

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Microtubule destruction induces tau liberation and its subsequent phosphorylation

Keywords: MT، میکروتوبول; NFT, neurofibrillary tangle; AD, Alzheimer’s disease; MT, microtubule; GSK3β, glycogen synthase kinase 3 beta; JNK, c-Jun N-terminal kinase; MEKK, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase; DMEM, Dulbecco’s modif

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Dynein at the kinetochore: Timing, Interactions and Functions

Keywords: MT، میکروتوبول; IFM, immunofluorescence microscopy; MT, microtubule; SAC, spindle assembly checkpointDynein; Mitosis; Kinetochores; Microtubules; Spindle; Checkpoint; Phosphorylation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Cell cycle-regulated expression and subcellular localization of a kinesin-8 member human KIF18B

Keywords: MT، میکروتوبول; MT, microtubule; KIF, kinesin superfamily; FBS, fetal bovine serum; PCR, polymerase chain reaction; RT-PCR, reverse transcription PCR; ORF, open reading frame; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis; EGFP, enhanced green fluor

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Probing Interactions between CLIP-170, EB1, and Microtubules

Keywords: MT، میکروتوبول; CLIP-170, cytoplasmic linker protein 170; MT, microtubule; + TIP, plus-end tracking protein; EB1, end-binding protein 1; EDC, 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide; GTP, guanosine 5′-triphosphate; MALDI, matrix-assisted laser desorption/ionizatio

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2010 سفارش ترجمه

Emerging new roles of the pre-Golgi intermediate compartment in biosynthetic-secretory trafficking

Keywords: MT، میکروتوبول; COP, coat protein; ERC, endocytic recycling compartment; IC, intermediate compartment; MT, microtubule; pcIC, pericentrosomal IC; PCMS, pericentrosomal membrane systemPolarized trafficking; Centrosome; Intermediate compartment; Endosome; Golgi bypass path

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

9-Ångström Structure of a Microtubule-Bound Mitotic Motor

Keywords: MT، میکروتوبول; K5, kinesin-5; MT, microtubule; EM, electron microscopy; CTT, C-terminal tail; PDB, Protein Data Bankkinesin; microtubule; cryo-electron microscopy; mitosis; cancer

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Microcystin-LR induces abnormal root development by altering microtubule organization in tissue-cultured common reed (Phragmites australis) plantlets

Keywords: MT، میکروتوبول; CMT, cortical microtubule; DAPI, 4′,6′-diamidino-2-phenylindole; MAP, microtubule-associated protein; MC-LR, microcystin-LR; MT, microtubule; PP1, type 1 serine–threonine protein phosphatase; PP2A, type 2A serine–threonine protein phosphatase; PPB, prepro

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

The role of meiotic cohesin REC8 in chromosome segregation in γ irradiation-induced endopolyploid tumour cells

Keywords: MT، میکروتوبول; MT, microtubule; ETCs, endopolyploid tumour cells; DSB, double-strand breakREC8; SGOL1; SGOL2; Irradiation; Tumour cells; Endopolyploidy; Chromosome segregation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Low molecular weight Aβ induces collapse of endoplasmic reticulum

Keywords: MT، میکروتوبول; AD, Alzheimer's disease; Aβ, β-amyloid; CLIMP-63, Cytoskeleton-linking membrane protein; ER, Endoplasmic reticulum; HDAC, Histone deacetylase; MT, Microtubule; MW, Molecular weight; Noc, Nocodazole; PDI, Protein disulfide isomerase; Tg, Thapsigargin; TSA,

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

A possible mechanism for controlling processive transport by microtubule-associated proteins

Keywords: MT، میکروتوبول; IMS, inter-microtubular spaces; MAP, microtubule-associated protein; MT, microtubule; NF, neurofilamentMAPs; Steric constraints; Processive transport; Inter-microtubular spaces

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Mutation in keratin 18 induces mitochondrial fragmentation in liver-derived epithelial cells

Keywords: MT، میکروتوبول; CB, cytochalasin B; DMSO, dimethyl sulfoxide; Drp1, dynamin-related protein 1; FRAP, fluorescence recovery; GFP, green fluorescent protein; IF, intermediate filament; K, keratin; MF, microfilament; MT, microtubule; OPA1, optic atrophy 1; WT, wild typeCyto

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Op18/Stathmin counteracts the activity of overexpressed tubulin-disrupting proteins in a human leukemia cell line

Keywords: MT، میکروتوبول; MT, microtubule; Op18, oncoprotein 18/stathmin; shRNA, short hairpin RNA.Mitosis; Microtubule-associated proteins; RNA interference; K562; Molecular chaperone; Transfection; GTP-binding Proteins; Protein binding; Protein folding; Protein turnover

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

NuSAP is degraded by APC/C–Cdh1 and its overexpression results in mitotic arrest dependent of its microtubules' affinity

Keywords: MT، میکروتوبول; APC/C, anaphase promoting complex/cyclosome; MT, Microtubule; NuSAP, nucleolar and spindle-associated protein; RNAi, RNA interferenceNuSAP; APC/C; Mitotic arrest; Degradation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

hNinein is required for targeting spindle-associated protein Astrin to the centrosome during the S and G2 phases

Keywords: MT، میکروتوبول; MT, Microtubule; MTOC, microtubule-organizing center; γ-TuRC, γ-tubulin ring complexes; siRN, small interfering RNANinein; Astrin; Centrosome; Cell cycle

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Arrestin Mobilizes Signaling Proteins to the Cytoskeleton and Redirects their Activity

Keywords: MT، میکروتوبول; GPCR, G protein-coupled receptor; MT, microtubule; WT, wild-type; SDSL, site-directed spin labeling; EPR, electron paramagnetic resonancearrestin; microtubules; ERK; Mdm2; G-protein coupled receptor

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Regulation of multiple cell cycle events by Cdc14 homologues in vertebrates

Keywords: MT، میکروتوبول; MT, microtubule; GLU, detyrosinated tubulin; WT, wild-type; PD, phosphatase-dead; RT, room temperatureCdc14; Cytokinesis; Abscission; exocyst; SNARE

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2007 سفارش ترجمه

Molecular Determination by Electron Microscopy of the Dynein–Microtubule Complex Structure

Keywords: MT، میکروتوبول; 2-D, two-dimensional; 3-D, three-dimensional; CTF, contrast transfer function; FSC, Fourier shell correlation; MT, microtubule; NSF, N-ethylmaleimide-sensitive fusion proteindynein; microtubule; motor protein; single particle analysis; cryoelectron micros

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2007 سفارش ترجمه

Clathrin light chain b is capable of affecting potently a major protein phosphatase from microtubules (MT-PP1)

Keywords: MT، میکروتوبول; MT, microtubule; PP, protein phosphatase; CL, clathrin light chainMicrotubules; Protein phosphatase-1; Clathrin light chain; Clathrin-coated vesicle; Intracellular vesicle transport

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Exploring the Mechanical Properties of Single Vimentin Intermediate Filaments by Atomic Force Microscopy

Keywords: MT، میکروتوبول; IF, intermediate filament; AFM, atomic force microscopy; ULF, unit-length filaments; MT, microtubule; TEM, transmission electron microscopyvimentin; intermediate filaments; atomic force microscopy; bending stiffness; axial sliding between dimmers; glutara

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Extracellular tau is toxic to neuronal cells

Keywords: MT، میکروتوبول; Aβ, beta amyloid peptide; AD, Alzheimer’s disease; EC, entorhinal cortex; MT, microtubule; NFT, neurofibrillary tangles; PHF, paired helical filamentsTau protein; Toxicity; Neuron degeneration

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Regulation of phosphorylation of tau by cyclin-dependent kinase 5 and glycogen synthase kinase-3 at substrate level

Keywords: MT، میکروتوبول; AD, Alzheimer disease; PHF, paired helical filaments; cdk5, cyclin-dependent protein kinase 5; GSK-3, glycogen synthase kinase-3; PDPK, proline-dependent protein kinase; MT, microtubule; PMSF, phenyl methyl sulfonyl fluorideAlzheimer disease; Glycogen syn

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه