Keywords: بانک داده پروتئین; GK, glucokinase; GKRP, glucokinase regulatory protein; F1P, fructose 1-phosphate; F6P, fructose 6-phosphate; SIS, sugar isomerase; PDB, Protein Data Bank; MD,, molecular dynamics; ED analysis, essential dynamics analysis; PCA, principle component analysis
مقالات ISI بانک داده پروتئین (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: بانک داده پروتئین; PDB, Protein Data Bank; MDS, molecular dynamics simulation; EM, energy minimization; MDS + EM, molecular dynamics simulation followed by energy minimizationDrug design; Molecular dynamics simulation; Interaction energy; Neural networks
Keywords: بانک داده پروتئین; RAS, renin-angiotensin system; AGT, angiotensinogen; GPCRs, G-protein coupled receptors; SSF, sequence-to-structure-to-function; Ang, angiotensin; PRR, (pro)renin receptor; pdb, Protein Data Bank; ACE, angiotensin converting enzyme; md, molecular dynamic;
Keywords: بانک داده پروتئین; ALDH, aldehyde dehydrogenase; HsALDH2, aldehyde dehydrogenase 2 from human; PDB, protein data bank; PaBADH, betaine aldehyde dehydrogenase from Pseudomonas aeruginosaNAD(P)+ specificity; Dual-coenzyme specificity; Conformational changes; Kinetic parameter
Keywords: بانک داده پروتئین; TLR4, Toll-like receptor 4; PDB, Protein Data Bank; cyno, cynomolgus monkey; LPS, lipopolysaccharide; CDR, complementarity-determining region; BLI, Bio-Layer Interferometry; SPR, surface plasmon resonance; PBS, phosphate-buffered saline; BSA, bovine serum
Keywords: بانک داده پروتئین; Leishmania mexicana; Quinazoline; Antiprotozoan activityPTR1, Pteridine reductase 1; DHFR, Dyhydrofolate reductase; IC50, Half inhibitory concentration; TAQ, Quinazoline-2,4,6-triamine; PDB, Protein Data Bank
Keywords: بانک داده پروتئین; IDPs, Intrinsically disordered proteins; IDPRs, Intrinsically disordered protein regions; PDB, Protein data bank; KL, Kullback-LeiblerIntrinsically disordered proteins; Secondary structure; Sequence complexity; Sequence composition; Charge; Hydrophobicity
Keywords: بانک داده پروتئین; Cockroach allergen; Bla g 4; Per a 4; Tyramine; Octopamine; AllergySe-Met, selenomethionine; PDB, Protein Data Bank; rmsd, root mean square derivative; HSQC NMR, heteronuclear single quantum correlation nuclear magnetic resonance; Tdp1, human tyrosyl-DNA
The crystal structure of Escherichia coli CsdE
Keywords: بانک داده پروتئین; PDB, Protein Data Bank; AU, asymmetric unit; rmsd, root-mean-square deviationSulfur-accepting protein; SufE superfamily; Sulfur utilization; Structural biology; X-ray crystallography; Protein structure
Difference in DNA-binding abilities of Fur-homolog DNA binding protein from Neisseria gonorrhoeae
Keywords: بانک داده پروتئین; Gonorrhea; TF; Computational modelling; Molecular docking simulations; Molecular dynamicsTF, Transcription Factor; PDB, Protein Data Bank; BLAST, Basic Local Alignment Search Tool; RMSD, Root Mean Squared Deviation; MD, Molecular Dynamics
NQO1 rs1800566 polymorph is more prone to NOx induced lung injury: Endorsing deleterious functionality through informatics approach
Keywords: بانک داده پروتئین; WT, Wild type; NQO1, NAD(P)H:quinone oxidoreductase 1; RMSD, Root mean square deviation; CUPSAT, Cologne University Protein Stability Analysis Tool; ΔΔG, unfolding energy; PDB, Protein data bank; MOE, Molecular Operating Environment; NPA, Nosé-Poincaré-An
Crystal structure and dynamics of Spt16N-domain of FACT complex from Cicer arietinum
Keywords: بانک داده پروتئین; PDB, protein data bank; MD, molecular dynamics; NMA, normal mode analysis; ENM, elastic network model; Spt16Nca, N-terminal domain of Spt16 from Cicer arietinum; Spt16Nsp, N-terminal domain of Spt16 from Schizosaccharomyces pombe; Spt16Nsc, N-terminal dom
Molecular insight into the activity of LasR protein from Pseudomonas aeruginosa in the regulation of virulence gene expression by this organism
Keywords: بانک داده پروتئین; PDB, Protein data bank; RMSD, Root mean squared deviation; OdDHL, N-(3-oxododecanoyl)-homoserine lactone; BLAST, Basic local alignment search toolLasR; DNA–protein interactions; Molecular Modeling; Molecular docking simulations; Binding interactions; Prot
A computational approach to determine susceptibility to cancer by evaluating the deleterious effect of nsSNP in XRCC1 gene on binding interaction of XRCC1 protein with ligase III
Keywords: بانک داده پروتئین; BER, base excision repair; DDG, Gibbs free energy change; GO, gene ontology; LIG3, ligase III; NER, nucleotide excision repair; NHEJ, non-homologous end joining; nsSNPs, non-synonymous single nucleotide polymorphisms; PDB, Protein Data Bank; RI, reliabili
The Corynebacterium pseudotuberculosis genome contains two formamidopyrimidine-DNA glycosylase enzymes, only one of which recognizes and excises 8-oxoguanine lesion
Keywords: بانک داده پروتئین; BER, base excision repair; AP, apurinic/apyrimidinic; MutM, formamidopyrimidine-DNA glycosylase; ROS, reactive oxygen species; H2TH, helix–two-turn–helix; PDB, Protein Data Bank; OD, optical density; IPTG, isopropyl b-d-thiogalactopyranoside; PAGE, polyac
A triad of molecular regions contribute to the formation of two distinct MHC class II conformers
Keywords: بانک داده پروتئین; aa, amino acid; HEL, hen egg lysozyme; IP, immunoprecipitate; mAb, monoclonal antibody; M1, α chain GxxxG motif 1; M2, α chain GxxxG motif 2; MHC, major histocompatibility complex; PDB, Protein Data Bank; TM, transmembrane domainMHC class II; Conformation
Structural characterization of Fis — A transcriptional regulator from pathogenic Pasteurella multocida essential for expression of virulence factors
Keywords: بانک داده پروتئین; RMSD, root mean squared deviation; PDB, Protein Data Bank; CG, conjugate gradient; H-bond, hydrogen bond; MD, molecular dynamicsTranscriptional regulator; Molecular modeling; Protein–DNA docking; Molecular dynamics simulations; Protein–DNA interactions
In silico identification of novel IL-1β inhibitors to target protein–protein interfaces
Keywords: بانک داده پروتئین; CADD, computer aided drug design; FRED, fast rigid exhaustive docking; IL-1β, interleukin-1 beta; IL-1R, interleukin-1 receptor; MOE, molecular operating environment; PDB, protein data bank; PLIF, protein ligand interaction fingerprints; QSAR, quantitativ
Populus deltoides Kunitz trypsin inhibitor 3 confers metal tolerance and binds copper, revealing a new defensive role against heavy metal stress
Keywords: بانک داده پروتئین; GFP, green fluorescent protein; KTI, Kunitz trypsin inhibitor; MD, molecular dynamics; PDB, Protein Data Bank; Populus deltoides KTI3, (PdKTI3); PI, proteinase inhibitor; RT-PCR, reverse transcription PCR; SD, synthetic defined; YPD, yeast potato dextrose
Groove binding mediated structural modulation and DNA cleavage by quinoline appended chalcone derivative
Keywords: بانک داده پروتئین; ADMQ, (E)-3-(anthracen-10-yl)-1-(6,8-dibromo-2-methylquinolin-3-yl)prop-2-en-1 one; ctDNA, calf thymus DNA; CD, circular dichromism; HEPES, N-[2-hydroxyethyl] piperazine-N-[2-ethanesulphonic acid]; PDB, protein data bank; OPLS, optimized potential for liq
Bacterial and algal orthologs of prostaglandin H2 synthase: novel insights into the evolution of an integral membrane protein
Keywords: بانک داده پروتئین; PGHS, prostaglandin H2 synthase; ORF, open reading frame; NSAID, non-steroidal anti-inflammatory drug; PDB, protein data bank; EGF, epidermal growth factor; 11R-HETE, 11R-hydroxy-5Z,8Z,12E,14Z-eicosatetraenoic acid; 15S-HETE, 15S-hydroxy-5Z,8Z,11Z,13E-eic
Identification and optimization of Escherichia coli GlmU inhibitors: An in silico approach with validation thereof
Keywords: بانک داده پروتئین; Escherichia coli; GlmU inhibitors; In silico; Computational screening; Acetyltransferase inhibitors; Lead optimizationMD, molecular dynamics; QSAR, quantitative structure–activity relationship; Ec, Escherichia coli; PDB, protein data bank; IC50, half maxi
A word of caution about biological inference – Revisiting cysteine covalent state predictions
Keywords: بانک داده پروتئین; Acc, prediction accuracies; FN, false negatives; FP, false positives; PDB, Protein Data Bank; TN, true negatives; TP, true positivesProtein prediction; Cysteine redox state; Protein structure; Prediction accuracies; Biological inference
Novel frame shift mutations (‘A’ deletion) observed in exon 9 of Wilms' tumor (WT1) gene in a patient reported with glomerulosclerosis
Keywords: بانک داده پروتئین; WT1, Wilms' tumor-suppressor gene-1; IHC, immunohistochemistry; TV, transcript variants; BLAST, Basic Local Alignment Search Tool; PDB, Protein Data Bank; SSCP, Single Strand Conformation Polymorphism; TERT, telomerase reverse transcriptase; FHL2, factor
Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase
Keywords: بانک داده پروتئین; hNV, human Norovirus; mNV, murine Norovirus; RdRp, RNA-dependent RNA-polymerase; PDB, protein data bank; NAF2, naphthalene-1,5-disulfonic acid; PPNDS, pyridoxal-5′-phosphate-6-(2′-naphthylazo-6′-nitro-4′,8′-disulfonate) tetrasodium saltNorovirus; Calicivi
Molecular recognition of Cullin3 by KCTDs: Insights from experimental and computational investigations
Keywords: بانک داده پروتئین; MD, molecular dynamics; RMSF, root mean square fluctuation; RMSD, root mean square deviation; RMSIP, root mean square inner product; ITC, isothermal titration calorimetry; PDB, Protein Data Bank; INC, insomniac protein; Cul3, Cullin3; CRL, Cullin RING lig
Functional characterization of diverse ring-hydroxylating oxygenases and induction of complex aromatic catabolic gene clusters in Sphingobium sp. PNB
Keywords: بانک داده پروتئین; RHO, ring-hydroxylating oxygenase; ET, electron transport; PAHs, polycyclic aromatic hydrocarbons; ISP, iron-sulfur protein; GR, glutathione reductase; PDB, Protein Data Bank; IPTG, isopropyl-β-thiogalactopyranoside; NR, non-redundant; NBB, n-butylboronat
Michael acceptor approach to the design of new salvinorin A-based high affinity ligands for the kappa-opioid receptor
Keywords: بانک داده پروتئین; Salvinorin A and B; Michael acceptor-type ligands; Kappa, delta, and mu opioid receptors; Molecular modelingDOR, δ-opioid receptor; GPCR, G protein-coupled receptor; KOR, κ-opioid receptor; MOR, μ-opioid receptor; TM, transmembrane; PDB, protein data bank
Structural Characterization of Anti-Inflammatory Immunoglobulin G Fc Proteins
Keywords: بانک داده پروتئین; IgG, immunoglobulin G; IVIG, intravenous immunoglobulin G; PDB, Protein Data Bank; HEK, human embryonic kidney; CHO, Chinese hamster ovary; LC, liquid chromatography; ESI, electrospray ionization; MS, mass spectrometry; MM, molecular mass; PEG, polyethyle
Identification of a Unique Fe-S Cluster Binding Site in a Glycyl-Radical Type Microcompartment Shell Protein
Keywords: بانک داده پروتئین; MCP, microcompartment; Grp, glycyl-radical propanediol; PDB, Protein Data Bank; EPR, electron paramagnetic resonance; ICP-MS, inductively coupled plasma mass spectrometry; NCS, noncrystallographic symmetrymetalloprotein; BMC-domain; glycyl-radical propane
Structural analyses of the permease like protein SoxT: A member of the sulfur compound metabolizing sox operon
Keywords: بانک داده پروتئین; PDB, Protein Data Bank; BLAST, Basic Local Alignment Search Tool; CVFF, Consistent Valence Force Field; r.m.s.d, Root Mean Squared DeviationSulfur oxidation; Molecular modeling; Membrane spanning region; Sulfur anion inducer
An assignment of intrinsically disordered regions of proteins based on NMR structures
Keywords: بانک داده پروتئین; IDP, intrinsically disordered protein; IDR, intrinsically disordered region; PDB, Protein Data Bank; NMR, Nuclear Magnetic Resonance; MCC, Matthews’s correlation coefficientIntrinsically disordered proteins; Deviations; Missing residues; Matthews’s correl
Investigations on the role of π–π interactions and π–π networks in eNOS and nNOS proteins
Keywords: بانک داده پروتئین; eNOS, endothelial Nitric Oxide Synthase; nNOS, neuronal Nitric Oxide Synthase; ASA, Accessible surface area; NCI, Non-canonical interactions; PDB, Protein Data Bank; SC, stabilization centerπ–π Interactions; eNOS; nNOS; Stability; Networks
CDR-H3 Diversity Is Not Required for Antigen Recognition by Synthetic Antibodies
Keywords: بانک داده پروتئین; CDR, complementarity-determining region; PDB, Protein Data Bank; TDRD3, tudor-domain-containing protein 3antibody library; phage display; protein engineering; affinity; specificity
Comparative genomics reveals ‘novel’ Fur regulated sRNAs and coding genes in diverse proteobacteria
Keywords: بانک داده پروتئین; Fur, Ferric uptake regulator; CDS, Coding domain sequence; FBS, Fur binding site; sRNA, small RNA; CRISPR, Clustered regularly interspaced pallindromic repeats; PDB, Protein data bank; IG, InterGenicNon-coding RNA; Intergenic; RyhB; Metabolic pathways; Fu
Potential monovalent cation-binding sites in aldehyde dehydrogenases
Keywords: بانک داده پروتئین; ALDH, aldehyde dehydrogenase; AMADH, ω-aminoaldehyde dehydrogenase; BADH, betaine aldehyde dehydrogenase; PDB, Protein Data Bank; hALDH2, human ALDH2; PaBADH, betaine aldehyde dehydrogenase from Pseudomonas aeruginosa; SoBADH, betaine aldehyde dehydrogena
Structural Insights into Transcriptional Repression by Noncoding RNAs That Bind to Human Pol II
Keywords: بانک داده پروتئین; Pol II, RNA polymerase II; ncRNA, noncoding RNA; cryo-EM, cryo-electron microscopy; PIC, pre-initiation complex; yPol II, yeast Pol II; hPol II, human Pol II; CTF, contrast transfer function; PDB, Protein Data Bank; CCD, charge-coupled device; EDTA, ethyl
Structural Basis of Signaling Blockade by Anti-IL-13 Antibody Lebrikizumab
Keywords: بانک داده پروتئین; IL-13, interleukin 13; CDR, complementarity-determining region; ICS, inhaled corticosteroids; PBS, phosphate-buffered saline; PDB, Protein Data Bank; SPR, surface plasmon resonancechronic asthma; allergy; paratope alanine scan; IL-4Rα competition
Towards dual antithrombotic compounds – Balancing thrombin inhibitory and fibrinogen GPIIb/IIIa binding inhibitory activities of 2,3-dihydro-1,4-benzodioxine derivatives through regio- and stereoisomerism
Keywords: بانک داده پروتئین; Antithrombotic; Thrombin inhibitor; GPIIb/IIIa; 2,3-dihydro-1,4-benzodioxine; Dual antithrombotic compound; MultitargetGPIIb/IIIa, glycoprotein IIb/IIIa; PDB, Protein Data Bank; DMAP, dimethylaminopyridine; DCM, dichloromethane; DMF, N,N-dimethylformamide
Janus: Prediction and Ranking of Mutations Required for Functional Interconversion of Enzymes
Keywords: بانک داده پروتئین; MSA, multiple sequence alignment; PDB, Protein Data Bank; PP, phenylpyruvate; DHDH, d-hydroxyisocaproate dehydrogenase; MDH, malate dehydrogenase; GDH, glutamate dehydrogenase; PEG, polyethylene glycolenzymology; protein engineering; directed evolution; c
Structural and Functional Analysis of the C-Terminal Domain of Nup358/RanBP2
Keywords: بانک داده پروتئین; NPC, nuclear pore complex; CTD, C-terminal domain; HIV-1, human immunodeficiency virus-1; CypA, cyclophilin A; β-ME, β-mercaptoethanol; SSRL, Stanford Synchrotron Radiation Lightsource; PDB, Protein Data Bank; ITC, isothermal titration calorimetry; PBS, p
Analyses of the Effects of All Ubiquitin Point Mutants on Yeast Growth Rate
Keywords: بانک داده پروتئین; PDB, Protein Data Bank; UBD, ubiquitin-binding domain; UIM, ubiquitin-interacting motif; UBA, ubiquitin-associated domain; WT, wild typefitness; structure; function; thermodynamic stability; sequence
Domain Swapping in the Cytoplasmic Domain of the Escherichia coli Rhomboid Protease
Keywords: بانک داده پروتئین; ecGlpG, Escherichia coli GlpG; ecGlpG-FL, full-length ecGlpG; ecGlpG-cyto, cytoplasmic domain of ecGlpG; ecGlpG-MD, membrane domain of ecGlpG; PDB, Protein Data Bank; psTatA, Providencia stuartii TatA; SEC, size-exclusion chromatography; Se-Met, selenomet
Arranged Sevenfold: Structural Insights into the C-Terminal Oligomerization Domain of Human C4b-Binding Protein
Keywords: بانک داده پروتئین; C4BP, C4b-binding protein; CCP, complement control domain protein; hC4BP, human C4b-binding protein; PDB, Protein Data Bank; SeMet, selenomethionine; SAD, single-wavelength anomalous dispersion; TEV, tobacco etch virusC4 binding protein, complement system
Unraveling Hidden Regulatory Sites in Structurally Homologous Metalloproteases
Keywords: بانک داده پروتئین; MMP, matrix metalloproteinase; APol, amphipol; SPR, surface plasmon resonance; PDB, Protein Data Bank; NNGH, N-arylsulfonyl α-aminohydroxamic acid; AHA, acetohydroxamic acid; XAS, X-ray absorption spectroscopy; HSQC, heteronuclear single quantum coherence
Effect of Mimetic CDK9 Inhibitors on HIV-1-Activated Transcription
Keywords: بانک داده پروتئین; LTR, long terminal repeat; TAR, trans-acting-responsive RNA element; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; CTD, C-terminal domain; GST, glutathione S-transferase; Pol II, polymerase II; PDB, Protein Data Bank; PBMC, peripheral blood mononuclear
Peptide Binding by Catalytic Domains of the Protein Disulfide Isomerase-Related Protein ERp46
Keywords: بانک داده پروتئین; EDTA, ethylenediaminetetraacetic acid; ER, endoplasmic reticulum; GST, glutathione S-transferase; PDB, Protein Data Bank; PDI, protein disulfide isomerase; Trx, thioredoxin; WT, wild typechaperone; substrate binding; peptide microarray; X-ray crystal stru
Molecular analysis of HEXA gene in Argentinean patients affected with Tay–Sachs disease: Possible common origin of the prevalent c.459 + 5A>G mutation
Keywords: بانک داده پروتئین; ACTR1a, alpha-centractin; AFAP, actin filament-associated protein; ALB, albumin; ME, Maximum Entropy; MLPA, Multiplex Ligation-dependent Probe Amplification; NN, Neural Network; PDB, Protein Data Bank; SD, Sandhoff diseaseGM2 gangliosidosis; Mutational an
Model for β-1,6-N-acetylglucosamine oligomer hydrolysis catalysed by DispersinB, a biofilm degrading enzyme
Keywords: بانک داده پروتئین; DspB, DispersinB; n, number of monomer unit; Ph, phenyl group; NAG, N-acetyl-glucosamine; PNAG, poly-β-d-(1,6)-N-acetyl-glucosamine; PDB, protein data bank; CAZy, carbohydrate-active enzymes database; GH, glycoside hydrolase; DP, degree of polymerisation;
Structural Insights into the Assembly and Shape of Type III Restriction–Modification (R–M) EcoP15I Complex by Small-Angle X-ray Scattering
Keywords: بانک داده پروتئین; SAXS, small-angle X-ray scattering; R–M, Restriction–Modification; TRD, target recognition domain; PDB, Protein Data Bank; SV, sedimentation velocity; BNL, Brookhaven National LaboratoryType III restriction enzyme; ATP hydrolysis; DNA translocation; DNA m