Keywords: آلکالوئیدهای پیررولیزیدین; Herbal drug; Arnebia benthamii; Pyrrolizidine alkaloids; Toxicity; Neelum Valley; HPLC;
مقالات ISI آلکالوئیدهای پیررولیزیدین (ترجمه نشده)
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Keywords: آلکالوئیدهای پیررولیزیدین; Liparis nervosa; Orchidaceae; Pyrrolizidine alkaloids; Cytotoxicity; Human colorectal cancer cell line; Autophagy; Apoptosis; MCJLHCBGPXQWLR-GKLPOLMESA-N;
Keywords: آلکالوئیدهای پیررولیزیدین; GS; Gynura segetum; PAs; Pyrrolizidine alkaloids; HSOS; hepatic sinusoidal obstruction syndrome; UPLC-Q-TOF/MS; Ultraperformance Liquid Chromatography -Quadrupole-Time-of-Flight / Mass Spectrometry; PLS-DA; partial least squares discrimination analysis; O
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; Acute toxicants; Genotoxic carcinogens; Hepatotoxic agents; Food; Food supplements; ANZFA; Australia New Zealand Food Authority; acute reference dose; ARfD; DHP; 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5[[H]]-pyrrolizine; BfR; Feder
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; Herbal infusion; Teas; Salads; Spices; Transfer rate; UHPLC-MS/MS;
Keywords: آلکالوئیدهای پیررولیزیدین; Food safety; China honey; Pyrrolizidine alkaloid; Pollen analysis; LC-MS analysis; PAs; pyrrolizidine alkaloids; UHPLC; ultra-high-performance liquid chromatography; MRM; multiple reaction monitoring; LOD; limit of detection; LOQ; limit of quantitation; R
Keywords: آلکالوئیدهای پیررولیزیدین; Horizontal natural products transfer; Contamination; Alkaloids; Berberine; Pyrrolizidine alkaloids; Strychnine; ACN; acetonitrile; HPLC; high performance liquid chromatography; MeOH; methanol; PAs; pyrrolizidine alkaloids; TFA; trifluoroacetic acid; UV; u
Keywords: آلکالوئیدهای پیررولیزیدین; HPLC-ESI-MS/MS; high performance liquid chromatography-electrospray ionization tandem mass spectrometry; PAs; pyrrolizidine alkaloids; HVOD; hepatic veno-occlusive disease; BfR; Bundesamt für Risikobewertung/German Federal Institute for Risk Assessment;
Keywords: آلکالوئیدهای پیررولیزیدین; Risk assessment; Pyrrolizidine alkaloids; (Herbal) teas; Plant food supplements; MOE; BMDL10; T25; T10; REP;
Keywords: آلکالوئیدهای پیررولیزیدین; Crotalaria; Pyrrolizidine alkaloids; Medicinal plants; ATR FTIR; DFT; QVCMHGGNRFRMAD-XFGHUUIASA-N;
Keywords: آلکالوئیدهای پیررولیزیدین; Horizontal transfer of natural products; Pyrrolizidine alkaloids; Plant derived commodities; Contamination; Senecio; Ragwort;
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; Hepatotoxicity; Metabolic activation; Reactive metabolites; Hepatic sinusoidal endothelial cell damage; Pyrrole-protein adductsCYP, cytochrome P450; DABA, 4-(dimethylamino)benzaldehyde; DHPA, dehydropyrrolizidine alkaloid; DHR, de
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; Relative potency factors; Risk assessment; Toxicity;
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; HPLC-ESI-MS/MS; Stable isotope labeled standard; Herbal tea; Infants; Pregnant and lactating women;
Keywords: آلکالوئیدهای پیررولیزیدین; Aboveground–belowground interactions; Insect–plant interactions; Leaf damage; Pyrrolizidine alkaloids; Root herbivory
Keywords: آلکالوئیدهای پیررولیزیدین; Plant toxins; Vegetation analysis; Cattle; Free grazing; Roughage; Ranking filter model; Piperidine alkaloids; Furanocoumarins; Pyrrolizidine alkaloids; Essential oils;
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; Risk assessment; Herbals; Margin of exposure; Herbal medicinal products; Safety; Carcinogenicity; Mutagenicity; ANZFA; The Australia New Zealand Food Authority; BfR; Federal Institute for Risk Assessment; BMDL10; benchmark dose lo
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; Monocrotaline; Microwave-assisted synthesis; Continuous-flow chemistry;
Keywords: آلکالوئیدهای پیررولیزیدین; Crotalaria pallida; Pyrrolizidine alkaloids; Usaramine; Eggs; Laying hens
Keywords: آلکالوئیدهای پیررولیزیدین; Astin; Endophytes; Hairy roots; Halogenase; Hypericin; Paclitaxel; Pyrrolizidine alkaloids; Terpene indole alkaloids; α-Tocopherol;
Keywords: آلکالوئیدهای پیررولیزیدین; PAs; pyrrolizidine alkaloids; MCT; monocrotaline; OCT1; organic cation transporter 1; MDCK; Madin-Darby canine kidney; MPP+; 1-methyl-4-phenylpyridinium; d-THP; d-tetrahydropalmatine; DHM; dehydromonocrotaline; CYP; cytochrome P450; ASP+; 4-(4-(dimethyl
Keywords: آلکالوئیدهای پیررولیزیدین; Orchidaceae; Liparis nervosa; Pyrrolizidine alkaloids; Nervogenic acid derivatives
Benzofurans, benzoic acid derivatives, diterpenes and pyrrolizidine alkaloids from Peruvian Senecio
Keywords: آلکالوئیدهای پیررولیزیدین; Asteraceae; Senecio; Benzofurans; Benzoic acid derivatives; Diterpenes; Pyrrolizidine alkaloids;
Pyrrole-protein adducts - A biomarker of pyrrolizidine alkaloid-induced hepatotoxicity
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; Pyrrole-protein adducts; Covalent binding; Target protein; Mechanism-based biomarker; Clinical diagnosis;
Survey of pyrrolizidine alkaloids in the tribe Lithospermeae (Boraginaceae) from Pan-Himalaya and their chemotaxonomic significance
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; Chemotaxonomy; Pan-Himalaya; Lithospermeae; HPLC;
Development of an in vitro screening method of acute cytotoxicity of the pyrrolizidine alkaloid lasiocarpine in human and rodent hepatic cell lines by increasing susceptibility
Keywords: آلکالوئیدهای پیررولیزیدین; Lasiocarpine (PubChem CID: 6321388); Loperamide hydrochloride (PubChem CID: 71420); bis(4-nitrophenyl)phosphate (PubChem CID: 255); DL-buthionine sulphoximine (PubChem CID: 21157); Rifampicin (PubChem CID: 5381226); Pyrrolizidine alkaloids; Cytotoxicity,
Relative potency of fifteen pyrrolizidine alkaloids to induce DNA damage as measured by micronucleus induction in HepaRG human liver cells
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; HepaRG; Genetic toxicology; Micronucleus test; Relative potency factor; Risk assessment; BMD; benchmark dose; CEF; critical effect size; CEDL; lower confidence interval of the critical effect dose; CEDU; upper confidence interval
PXR: Structure-specific activation by hepatotoxic pyrrolizidine alkaloids
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; Nuclear receptors; PXR; Echimidine;
Natural occurrence of genotoxic and carcinogenic alkenylbenzenes in Indonesian jamu and evaluation of consumer risks
Keywords: آلکالوئیدهای پیررولیزیدین; Alkenylbenzenes; Jamu; Margin of exposure (MOE); Risk assessment; BMDL10; lower confidence limit of the benchmark dose resulting in a 10% extra cancer incidence; EDI; Estimated daily intake; EFSA; European Food Safety Authority; ILSI; International Life S
Is comfrey root more than toxic pyrrolizidine alkaloids? Salvianolic acids among antioxidant polyphenols in comfrey (Symphytum officinale L.) roots
Keywords: آلکالوئیدهای پیررولیزیدین; Symphytum officinale L.; Phenolic compounds; Salvianolic acids; Antioxidant activity; Pyrrolizidine alkaloids;
Total syntheses of heliotridane and pseudoheliotridane through nitrodiene-acrylate 6Ï-electrocyclization/[3+2] cycloaddition
Keywords: آلکالوئیدهای پیررولیزیدین; Nitrodiene; 6Ï-electrocyclization/[3+2] cycloaddition; Total synthesis; Pyrrolizidine alkaloids; Heliotridane; Pseudoheliotridane;
Senecio angustifolius as the major source of pyrrolizidine alkaloid contamination of rooibos tea (Aspalathus linearis)
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; Aspalathus linearis; Rooibos tea; Senecio angustifolius; LC-MS/MS;
Integrative analysis of hepatic microRNA and mRNA to identify potential biological pathways associated with monocrotaline-induced liver injury in mice
Keywords: آلکالوئیدهای پیررولیزیدین; Monocrotaline; Liver injury; miRNA; mRNA; Integrative analysis; Phagosome; PAs; Pyrrolizidine alkaloids; MCT; Monocrotaline; miRNA; microRNA; ALT/AST; alanine/aspartate aminotransferase; TBil; total bilirubin; HSOS; hepatic sinusoidal obstruction syndrome
Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice
Keywords: آلکالوئیدهای پیررولیزیدین; ALT; Alanine aminotransferase; ActD; Actinomycin D; CYP; Cytochrome P450; CQ; Chloroquine; Drp1; Dynamin-related protein 1; DHPAs; Dehydropyrrolizidine alkaloids; DHR; dehydroretronecine; EM; Electron microscopy; GSH; Glutathione; GAPDH; Glyceradehyde-3-p
Comparative HILIC/ESI-QTOF-MS and HPTLC studies of pyrrolizidine alkaloids in flowers of Tussilago farfara and roots of Arnebia euchroma
Keywords: آلکالوئیدهای پیررولیزیدین; PAs; pyrrolizidine alkaloids; PANOs; pyrrolizidine alkaloid-N-oxides; TF; Tussilago farfara; AE; Arnebia euchroma; HILIC; hydrophilic interaction liquid chromatography; ESI-QTOF-MS; electrospray ionization quadruple time-of-flight mass spectrometry; TCM;
Simultaneous identification and quantification of polymethoxyflavones, coumarin and phenolic acids in Ageratum conyzoides by UPLC-ESI-QToF-MS and UPLC-PDA
Keywords: آلکالوئیدهای پیررولیزیدین; Ageratum conyzoides; Polymethoxyflavones; Pyrrolizidine alkaloids; Coumarin; Phenolic acids;
Pyrrolizidine alkaloids from Cynoglossum columnae Ten. (Boraginaceae)
Keywords: آلکالوئیدهای پیررولیزیدین; Cynoglossum columnae; Boraginaceae; Pyrrolizidine alkaloids; β-Arbutin;
Activity of pyrrolizidine alkaloids against biofilm formation and Trichomonas vaginalis
Keywords: آلکالوئیدهای پیررولیزیدین; Usaramine; Monocrotaline; Pyrrolizidine alkaloids; Biological activity
Clivorine, an otonecine pyrrolizidine alkaloid from Ligularia species, impairs neuronal differentiation via NGF-induced signaling pathway in cultured PC12 cells
Keywords: آلکالوئیدهای پیررولیزیدین; Clivorine; Ligularia species; Pyrrolizidine alkaloids; Neurotoxicity; Neuronal differentiation; Protein kinase BAkt, protein kinase B; CREB, cAMP response element-binding protein; DHP, dehydro-PA; Erk, extracellular signal-regulated kinase; GAPDH, glycera
Herbivory and fitness components in an introgressive hybrid swarm of Senecio hercynicus and S. ovatus (Compositae, Senecioneae)
Keywords: آلکالوئیدهای پیررولیزیدین; Genetic swamping; Hybrid fitness; Hybridisation; Phenology; Pyrrolizidine alkaloids
A fast and simple LC-ESI-MS/MS method for detecting pyrrolizidine alkaloids in honey with full validation and measurement uncertainty
Keywords: آلکالوئیدهای پیررولیزیدین; Plant toxins; Phytotoxins; Food safety; Dilute-and-shoot; Method validation; PAs; pyrrolizidine alkaloids; SEN; senecionine; SEN-N; senecionine-N-oxide; ECH; echimidine; INT; intermedine; LYC; lycopsamine; RET; retrorsine; MCT; monocrotaline; RET-N; retro
Aqueous extract of Senecio candicans DC induce liver and kidney damage in a sub-chronic oral toxicity study in Wistar rats
Keywords: آلکالوئیدهای پیررولیزیدین; Senecio candicans; Sub-chronic toxicity; Pyrrolizidine alkaloids; Aqueous extract; Albino rats; Safety evaluation;
UPLC–MS/MS method for determination of selected pyrrolizidine alkaloids in feed
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; Feeds; Plant toxins; UPLC–MS/MS; QuEChERS
UPLC TOF MS for sensitive quantification of naturally occurring pyrrolizidine alkaloids in Petasites hybridus extract (Ze 339)
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; UPLC; Mass spectroscopy;
Modulatory effect of Senecio brasiliensis (Spreng) Less. in a murine model of inflammation induced by carrageenan into the pleural cavity
Keywords: آلکالوئیدهای پیررولیزیدین; EtOAc; ethyl acetate fraction; ADA; adenosine-deaminase; AF; alkaloid fraction; CE; crude extract of flowers; CONCEA; National Council of Animal Experimentation Control; DCM; dichloromethane fraction; DCQs; mixture of dicaffeoylquinic acids; Cg; carrageen
Prenatal exposure to integerrimine N-oxide enriched butanolic residue from Senecio brasiliensis affects behavior and striatal neurotransmitter levels of rats in adulthood
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; Senecio; Offspring; Rats; Neurobehavioral
Sesquiterpenes, flavonoids, shikimic acid derivatives and pyrrolizidine alkaloids from Senecio kingii Hook
Keywords: آلکالوئیدهای پیررولیزیدین; Asteraceae; Senecio kingii; Eremophilanolides; Shikimic acid derivatives; Flavonoids; Pyrrolizidine alkaloids; Structure-activity;
New sources of lycopsamine-type pyrrolizidine alkaloids and their distribution in Apocynaceae
Keywords: آلکالوئیدهای پیررولیزیدین; Apocynaceae; Pyrrolizidine alkaloids; Pharmacophagy; Arctiinae; Sphingidae; Danainae; Echites; ParsonsiaGC-MS, gas chromatography mass spectroscopy; LC-MS, liquid chromatography mass spectroscopy; MRM, multiple reaction monitoring scan; NMR, nuclear magne
Are effects of common ragwort in the Ames test caused by pyrrolizidine alkaloids?
Keywords: آلکالوئیدهای پیررولیزیدین; Ragwort; Pyrrolizidine alkaloids; Quercetin; Ames test; LC-MS/MS
Effective application of freezing lipid precipitation and SCX-SPE for determination of pyrrolizidine alkaloids in high lipid foodstuffs by LC-ESI-MS/MS
Keywords: آلکالوئیدهای پیررولیزیدین; Pyrrolizidine alkaloids; High lipid foodstuffs; Freezing lipid precipitation; SCX-SPE; LC-ESI-MS/MS-MRM