Keywords: Antibody aggregate; Aggregate removal; Hydrophobic interaction chromatography (HIC); Hydroxyapatite (HA); Mixed-mode resin; Polyethylene glycol (PEG); mAb; monoclonal antibody; bsAb; bispecific antibody; scFv; single-chain variable fragment; CHO; Chinese
مقالات ISI (ترجمه نشده)
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Keywords: MBL; mannose binding lectin; APC; antigen presenting cell; DAF; decay accelerating factor; C3aR; C3a receptor; SLE; systemic lupus erythematosus; MAC; membrane attack complex; IRI; ischemia-reperfusion injury; scFv; single chain variable fragment; sCR1; s
Keywords: scFv; VH3; VL3; Hydrophobic cores; Solubility;
Keywords: ABC; Accelerated blood clearance; BBB; Blood brain barrier; CH; Cholesterol; CHEMS; Cholesteryl hemisuccinate; DOPE; 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine; DPPC; 1,2-dipalmitoyl-sn-glycero-3-phosphocholine; DPPG2; 1,2-dipalmitoyl-sn-glycero-3-phos
Keywords: bsAb; bispecific antibody; CAR; chimeric antigen receptor; CDN; cyclic dinucleotides; CTL; cytotoxic T lymphocyte; CTLA-4; cytotoxic T-lymphocyte-associated protein 4; GM-CSF; granulocyte-monocyte colony stimulating factor; IR; irradiation; PD-1; Programm
Keywords: ScFv; Catalytic antibody; Expression vector; Mammalian expression; Bacterial expression; AP; alkaline phosphatase; BHQ; black hole quencher; BsAb; bispecific antibody; CD; circular dichroism; DTT; dithiothreitol; ELISA; enzyme-linked immunosorbent assay;
Keywords: BCA; bicinchoninic acid; CDR1; 2complementarity determining regions 1, 2; CFA; complete Freund's adjuvant; Cκ; constant kappa light chain; Cλ; constant lambda light chain; DH; heavy diversity; DNase; deoxyribonuclease; ELISA; direct enzyme-linked immu
Immunochemical techniques for multianalyte analysis of chemical residues in food and the environment: A review
Keywords: Immunoassay; Multianalyte analysis; Antibody; Food; Environmental; BSA; bovine serum albumin; CAMM; computer-assisted molecular modeling; CCD; charge-coupled device; CDR; complementarity determining region; CR; cross-reactivity; CoMFA; comparative molecu
Keywords: mAb; monoclonal antibody; scFv; single-chain variable-fragment; Fc; crystallizable fragment; PK; pharmacokinetic; SPR; surface plasmon resonance; HRV; human rhinovirus; Drugs of abuse; Cocaine; Monoclonal antibody; scFv-Fc; Cocaine overdose;
Keywords: OPMA-N; of oligosaccharide-producing multifunctional amylase, N isoform; ÎOPMA-N; OPMA-N lacking the N-terminal domain; MFAs; multifunctional amylases; scFv; single-chain variable fragment; VH; heavy light; VL; light chains; OPMA-MR; recombinants of OPMA
Keywords: IgG; Immunoglobulin G; VH; Heavy chain variable; CH; Heavy chain constant; VL; Light chain variable; CL; Light chain constant; Fab; Antigen-binding fragment; Fc; Crystallizable fragment; CDR; Complementarity determining region; Fv; Variable fragment; scFv
Keywords: dAb; domain antibody; D.A.R.T's; Disposable Automation Research Tips; HlyE; Hemolysin E; MS; mass spectrophotometry; MSIA; mass spectrometry immunoassay; scFv; single-chain variable fragment; Ub; ubiquitin; Domain antibodies; Disposable Automation Researc
Keywords: scFv; single-chain variable fragment; 6XHis; hexahistidine; BCCP; biotin carboxyl carrier protein; gpD; bacteriophage lambda head protein D; IPTG; isopropyl β-d-1-thiogalactopyranoside; HRP; horseradish peroxidase; scFv; Immobilization; Biotin; Streptavi
Keywords: scFv; single-chain antibody fragment; Loxosceles; Venom; Diabody; Neutralization; Spider; Antivenom;
Keywords: Schistosoma japonicum; Schistosomule; Phage-display; Protein microarray; Single-chain Fv antibody; scFv; Buffalo; China;
Keywords: Alzheimer's disease; Toxic tau aggregates; Phage display; Brain tissue; Biomarker; scFv; Oligomeric tau; Antibody fragments; Immunotherapy;
Keywords: Antibodies; Immunoconjugates; Immunotoxins; Ab; antibody; Ag; antigen; ADCC; antibody-dependent cell mediated cytotoxicity; ALL; acute lymphoblastic leukemia; AML; acute myeloid leukemia; AKT; protein kinase B; APC; antigen-presenting cell; Apo2L/TRAIL; t
Keywords: Variable domain of heavy-chain antibody; Inhibition of protein misfolding and aggregation; Protein misfolding diseases; Amyloidoses; VHH; Nanobody; Ab; antibody; Aβ; amyloid β-peptide; AD; Alzheimer's disease; ANS; anilino naphthalene-sulfonic acid; AP;
Keywords: Phage antibody library; Cell-based selection; BSA; bovine serum albumin; CEA; carcino embryonic antigen; ELISA; enzyme-linked immunosorbent assay; FACS; fluorescence-activated cell sorting; HRP; horseradish peroxidase; PBS; phosphate-buffered saline; PEG;
Keywords: aa; amino acid; AMC; anti-modified citrulline; HRP; horseradish peroxidase; LC; liquid chromatography; MS; mass spectrometry; PAD; peptidylarginine deiminase; RA; rheumatoid arthritis; scFv; single-chain variable fragment; VSV-G; vesicular stomatitis viru
Keywords: Immunochemical analysis; Recombinant antibodies; ScFv; ELISA; Tetraconazole; Fungicide residues; Fruit juices;
Keywords: Measles virus; Virus retargeting; Neutralization; Monoclonal antibodies; Human serum; Oncolytic virotherapy; scfv; Ligand display; Cancer;
Keywords: AD; Alzheimer's disease; PD; Parkinson's disease; HD; Huntington's disease; CJD; Creutzfeld-Jacob disease; mAb; monoclonal antibody; scFv; single-chain Fv; VH; variable domain of the heavy chain; VL; variable domain of the light chain; VHH; variable dom
Keywords: scFv; single chain antibody fragment; PBS/NCS; phosphate-buffered saline/neonatal calf serum; POD; horseradish peroxidase; TMB; tetramethylbenzidine; FITC; fluorescein isothiocyanate; NHS; N-hydroxysuccinimide; IPTG; isopropyl-β-d-thiogalactopyranoside;
Keywords: E. coli; Escherichia coli; NMR; nuclear magnetic resonance; PEP; phosphoenolpyruvate; scFv; single chain Fv; BPTI; bovine pancreatic trypsin inhibitor; LYZ; lysozyme C; MWCO; molecular weight cut-off; GSH; reduced glutathione; GSSG; oxidized glutathione;
Keywords: Human scFv; In vitro maturation; Scorpion toxin; aa; amino acid(s); CDR; complementarity determining region (s); C. limpidus; Centruroides limpidus limpidus Karsh; Cll1 and Cll2; toxins 1 and 2 from Centruroides limpidus limpidus venom; C. noxius; Centru
Keywords: HTP; high throughput; scFv; single chain Fv; Fab; fragment antigen-binding; IRES; internal ribosome entry site; VH; heavy chain variable regions; EBNA-1; Epstein-Barr virus nuclear antigen 1; CMV; cytomegalovirus.; Adenovirus expression system; Mammalia
Keywords: scFv; single-chain fragment variable; Fab; fragment antigen binding; PBMC; peripheral blood mononuclear cell; V; variable; VH; variable heavy chain; VL; variable light chain; Vκ; variable kappa light chain; Vλ; variable lambda light chain; PPE; periplas
Keywords: ANK; ankyrin repeat; CDR; complementarity-determining region; DAPI; 4â²,6â²-diamidino-2 phenyleindole; EGFP; enhanced green fluorescent protein; FLIM; fluorescence lifetime imaging microscopy; FRET; Förster resonant energy transfer; GK; gankyrin; GST;
Molecular characterization of single-chain antibody variable fragments (scFv) specific to Pep27 from Streptococcus pneumoniae
Keywords: Streptococcus pneumoniae; Pep27; scFv; Affinity; Epitope;
A novel lentiviral scFv display library for rapid optimization and selection of high affinity antibodies
Keywords: Agtuzumab; Lentivirus scFv display library; Hotspot mutagenesis; Optimization library; AGR2; anterior gradient 2; CDR; Complementary Determining Regions; CopGFP; copepod Pontellina plumata Green Fluorescence Protein; scFv; single chain fragment variable;
Discovery of human scFvs that cross-neutralize the toxic effects of B. jararacussu and C. d. terrificus venoms
Keywords: Bothrops jararacussu; Crotalus durissus terrificus; scFv; Antivenom; Phage display; Indirect hemolysis; Plasma-clotting;
Generation of a T cell receptor (TCR)-like single domain antibody (sDAb) against a Mycobacterium Tuberculosis (Mtb) heat shock protein (HSP) 16kDa antigen presented by Human Leukocyte Antigen (HLA)-A*02
Keywords: ABTS; 2,2â²-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt; APC; Antigen presenting cells; APD; Antigen Phage Display; BSA; bovine serum albumin; DAb; human domain antibody; ELISA; enzyme-linked immunosorbent assays; Fv; Fragment varia
Therapeutic treatment with scFv-PLGA nanoparticles decreases pulmonary fungal load in a murine model of paracoccidioidomycosis
Keywords: Paracoccidioidomycosis; Paracoccidioides brasiliensis; scFv; PLGA;
Combination of novel DR5 targeting agonistic scFv antibody TR2-3 with cisplatin shows enhanced synergistic antitumor activity in vitro and in vivo
Keywords: DR5; death receptor 5; DR4; death receptor 4; TNF; tumor necrosis factor; TRAIL; TNF-related apoptosis inducing ligand; scFv; single chain fragment variable; MTT; methyl thazoy terazolium; IPTG; isopropyl β-D-1-thiogalactopyranoside; PBS; phosphate buffe
Construction of humanized anti-HER2 single-chain variable fragments (husFvs) and achievement of potent tumor suppression with the reconstituted husFv-Fdt-tBid immunoapoptotin
Keywords: HER2; Immunogenicity; Humanized scFv; Immunoapoptotin; Targeted cancer therapy; Apoptosis; HER2; human epidermal growth factor receptor 2; scFv; single-chain variable fragment; husFv; humanized e23sFv; VL; light chain variable region; VH; heavy chain vari
T cell engaging bispecific antibody (T-BsAb): From technology to therapeutics
Keywords: CRS; cytokine release syndrome; CTL; cytotoxic T lymphocyte; EC50; half maximal effective concentration; Fc; fragment crystallizable; ICI; immune checkpoint inhibitor; pMHC; peptide-major histocompatibility complex; scFv; single chain variable fragment; T
ScFv-modified graphene-coated IDE-arrays for 'label-free' screening of cardiovascular disease biomarkers in physiological saline
Keywords: scFV; Graphene; Biosensor; Cardiovascular; Electrical sensing; Physiological buffer;
Evaluation of in vitro refolding vs cold shock expression: Production of a low yielding single chain variable fragment
Keywords: Inclusion bodies; Single chain variable fragment; In vitro protein refolding; Cold shock; Disulfide bridge; Tissue factor; Fusion partner; Codon Adaptation Index; CAI; Dimethyl sulfoxide; DMSO; E.coli Codon Usage Analyzer; ECUA; Escherichia coli; E.coli;
Production and characterization of a novel site-specific-modifiable anti-OX40-receptor single-chain variable fragment for targeted drug delivery
Keywords: Single chain antibody(scFv); OX40; Antibody drug conjugate; Drug delivery; Internalization; Thermal stability of antibody; OX40L; OX40 lignad; scFv; single-chain variable fragment; scFvC; scFv carrying a C-terminal cysteine residue; IκB; nuclear factor o
Docetaxel loaded immunonanoparticles delivery in EGFR overexpressed breast carcinoma cells
Keywords: Albumin; scFv; Cell proliferation; Chemotherapy; Drug delivery; Targeted nanoparticle;
Differential effects of apoE and apoJ mimetic peptides on the action of an anti-Aβ scFv in 3xTg-AD mice
Keywords: Alzheimer's disease; Immunotherapy; Apolipoproteins; scFv; 3xTg-AD;
Reformation in chimeric antigen receptor based cancer immunotherapy: Redirecting natural killer cell
Keywords: NK cell; natural killer cell; IFN-γ; interferon-γ; IL; interleukin; TNF-α; tumor necrosis factor-α; CCL; C-C motif ligand; GM-CSF; granulocyte-macrophage colony-stimulating factor; ADCC; antibody dependent cell-mediated cytotoxicity; TRAIL; TNF-relate
Engineering of a novel zipFv using leucine zipper motif against rabies virus glycoprotein G with improved protection potency in vivo
Keywords: Rabies; scFv; zipFv; Leucine zipper; RFFIT;
Functional and immuno-reactive characterization of a previously undescribed peptide from the venom of the scorpion Centruroides limpidus
Keywords: aa; amino acid; Cll; Centruroides limpidus; Cll1m; toxin 1 from C. limpidus; Cll2; Toxin 2 from C. limpidus and Cl13 Toxin 13 from C.limpidus; hNav; human voltage gated sodium channels; scFv; single chain antibody fragment; Antibody; Centruroides limpidus
Research paperRational design of low immunogenic anti CD25 recombinant immunotoxin for T cell malignancies by elimination of T cell epitopes in PE38
Keywords: ADA; anti-drug antibodies; ATL; adult T cell leukemia; dsFv; disulfide stabilized variable fragment; PE38; Pseudomonas exotoxin A; PBMC; peripheral mononuclear cells; RIT; recombinant immunotoxin; R-PE; phycoerythrin-tagged anti-CD25 antibody; scFv; singl
Virtual mutation and directional evolution of anti-amoxicillin ScFv antibody for immunoassay of penicillins in milk
Keywords: ScFv; Penicillins; Directional evolution; Virtual mutation; Mutant; Milk;
CAR T-cell therapy for lung cancer and malignant pleural mesothelioma
Keywords: ACT; adoptive cell therapy; ADC; adenocarcinoma; ALK; anaplastic lymphoma kinase; CAF; cancer-associated fibroblast; CAR; chimeric antigen receptor; CEA; carcinoembryonic antigen; CTLA-4; cytotoxic T-lymphocyte associated protein 4; DNR; dominant negative
Development of novel antigen receptors for CAR T-cell therapy directed toward solid malignancies
Keywords: CAR; chimeric antigen receptor; HLA; human leukocyte antigen; MHC; major histocompatibility complex; NCI CTCAE; National Cancer Institute Common Terminology Criteria for Adverse Events; NSG; NOD scid gamma; PBL; peripheral blood lymphocytes; RECIST; Respo
Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2
Keywords: MSP2; merozoite surface protein 2; GPI; glycosylphosphatidyl inositol; mAb; monoclonal antibody; IFA; immunofluorescence assay; SPR; surface plasmon resonance; Fv; variable fragment; scFv; single-chain Fv; ITC; isothermal titration calorimetry; VH; variab