Keywords: مهار انتخابی; 2,3-Diaryl acrylonitrile; Cyano group; Antitumor activity; Selective inhibition; Migration;
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Keywords: مهار انتخابی; Folate pathway; Trypanosomatids; Structure-based drug design; Selective inhibition; Enzyme inhibitor; Anti-parasitic drug; PTR1; Pteridine reductase 1; DHFR; Dihydrofolate reductase; dUMP; Deoxyuridine monophosphate; dTMP; Deoxythymidine monophosphate; hD
Keywords: مهار انتخابی; Soil; Fungi; Nitrous oxide; Selective inhibition; Cattle overwintering; Oxygen availability
Keywords: مهار انتخابی; Nitric oxide synthase; Selective inhibition; Thiophenecarboximidamide; Heme; Tetrahydrobiopterin; Protein crystallography
Keywords: مهار انتخابی; Inhibitory control; Selective inhibition; Electrical neuroimaging; EEG topography; Electrical sources;
Keywords: مهار انتخابی; Selective inhibition; Development; Response activation; Response inhibition; EMG; Laplacian ERPs
Keywords: مهار انتخابی; Substrate-induced respiration; SIR; Selective inhibition; Biovolume measurements; Microbial biomass; Community structure
Keywords: مهار انتخابی; Racemic trisubstituted benzocycloheptane derivatives; Synthetic inhibitors; Selective inhibition; M1 aminopeptidases; M28 aminopeptidases;
Novel (S)-1,3,4,12a-tetrahydropyrazino[2,1-c][1,4]benzodiazepine-6,12(2H,11H)-dione derivatives: Selective inhibition of MV-4-11 biphenotypic B myelomonocytic leukemia cells' growth is accompanied by reactive oxygen species overproduction and apoptosis
Keywords: مهار انتخابی; Tricyclic benzodiazepines; Selective inhibition; Biphenotypic B myelomonocytic leukemia; Reactive oxygen species overproduction; Apoptosis; Anticancer activity;
Phenoxypropanolamine derivatives as selective inhibitors of the 20S proteasome β1 and β5 subunits
Keywords: مهار انتخابی; Phenoxypropanolamine; Thiophene; 20S proteasome; ChT-L, T-L and PA activities; Selective inhibition; In silico structure-based docking;
Testing the physiological plausibility of conflicting psychological models of response inhibition: A forward inference fMRI study
Keywords: مهار انتخابی; BOLD; blood-oxygen-level dependent; DLPFC; dorsolateral pre-frontal cortex; dmFC; dorsomedial frontal; fMRI; functional magnetic resonance imaging; FP; fixation point; GNG; go/nogo; HRF; hemodynamic response function; IFG; inferior frontal gyrus; IPL; inf
Indolyl-3-ethanone-α-thioethers: A promising new class of non-toxic antimalarial agents
Keywords: مهار انتخابی; Indolyl-3-ethanone-α-thioethers; Plasmodium falciparum; Antimalarial; Selective inhibition
Distinct novel quinazolinone exhibits selective inhibition in MGC-803 cancer cells by dictating mutant p53 function
Keywords: مهار انتخابی; Mutant p53; Selective inhibition; Quinazolinone; Apoptosis;
Inhibition of CYP1 by berberine, palmatine, and jatrorrhizine: Selectivity, kinetic characterization, and molecular modeling
Keywords: مهار انتخابی; AHH; benzo(a)pyrene hydroxylase; P450, CYP; cytochrome P450; ECOD; 7-ethoxycoumarin O-deethylation; EROD; 7-ethoxyresorufin O-deethylation; MROD; 7-methoxyresorufin O-demethylation; Berberine; CYP1B1; Selective inhibition;
Chronic aspirin via dose-dependent and selective inhibition of cardiac proteasome possibly contributed a potential risk to the ischemic heart
Keywords: مهار انتخابی; Aspirin; Selective inhibition; Cardiac proteasome; A potential risk; Ischemic rat heart
Syntheses and structure-activity relationship studies of N-substituted-β-d-glucosaminides as selective cytotoxic agents
Keywords: مهار انتخابی; Glucosaminides; Cinnamoyl; Urea; Thiosemicarbazone; Selective inhibition;
Discovery of 1-[4-(N-benzylamino)phenyl]-3-phenylurea derivatives as non-peptidic selective SUMO-sentrin specific protease (SENP)1 inhibitors
Keywords: مهار انتخابی; SENP1; Non-peptidic inhibitors; HIF-1; deSUMOylation; Selective inhibition
The adenosine deaminases of Plasmodium vivax and Plasmodium falciparum exhibit surprising differences in ligand specificity
Keywords: مهار انتخابی; Computational modeling; Drug design; Ligand recognition; Selective inhibition; Site-directed mutagenesis; Adenosine deaminase
Novel coumarins and 2-thioxo-coumarins as inhibitors of the tumor-associated carbonic anhydrases IX and XII
Keywords: مهار انتخابی; Carbonic anhydrase; Coumarin; Transmembrane isoform; Tumor-associated enzyme; Selective inhibition;
The FungiResp method: An application of the MicroResp⢠method to assess fungi in microbial communities as soil biological indicators
Keywords: مهار انتخابی; Substrate-induced respiration; Selective inhibition; MicroRespâ¢; Soil microbial catabolic structure; Soil fungal catabolic structure;
Inhibition of monoamine oxidase by 8-[(phenylethyl)sulfanyl]caffeine analogues
Keywords: مهار انتخابی; Monoamine oxidase; Sulfanylcaffeine; Sulfinylcaffeine; Reversible inhibition; Selective inhibition; Caffeine; Structure–activity relationship
Selectivity of 3′-O-methylponkoranol for inhibition of N- and C-terminal maltase glucoamylase and sucrase isomaltase, potential therapeutics for digestive disorders or their sequelae
Keywords: مهار انتخابی; α-Glucosidase inhibitors; 3′-O-Methylponkoranol; Maltase glucoamylase; Sucrase isomaltase; Selective inhibition; Therapeutics of digestive disorders
N-(Pyridin-3-yl)benzamides as selective inhibitors of human aldosterone synthase (CYP11B2)
Keywords: مهار انتخابی; CYP11B2; Aldosterone synthase; Selective inhibition; Metyrapone; Aldosterone; Congestive heart failure; Myocardial fibrosis;
Role of the side chain stereochemistry in the α-glucosidase inhibitory activity of kotalanol, a potent natural α-glucosidase inhibitor
Keywords: مهار انتخابی; Kotalanol; α-Glucosidase inhibitor; Salacia; SAR study; Selective inhibition
La 11β-hydroxystéroïde déshydrogénase de type 1 - 2e partie Inhibition sélective pour traiter les anomalies métaboliques associées à l'obésité
Keywords: مهار انتخابی; Obésité abdominale; syndrome métabolique; cortisol; 11β-hydroxysteroïde déshydrogénase de type 1; inhibition sélective; diabète de type 2; Abdominal obesity; metabolic syndrome; cortisol; 11β-hydroxysteroid dehydrogenase type 1; selective inhibi
Structural analysis of PI3-kinase isoforms: Identification of residues enabling selective inhibition by small molecule ATP-competitive inhibitors
Keywords: مهار انتخابی; PI3-Kinase isoforms; Selective inhibition; ATP-competitive inhibitors; Molecular modelling; Docking;
Quantitative assessment of the fungal contribution to microbial tissue in soil
Keywords: مهار انتخابی; Direct microscopy; Selective inhibition; Ergosterol; PLFA; 16:1Ï5; 18:1Ï9; 18:2Ï6,9; Saprotrophic fungi; Biotrophic fungi; Glucosamine; Muramic acid;
Inhibition of malaria parasite blood stages by tyrocidines, membrane-active cyclic peptide antibiotics from Bacillus brevis
Keywords: مهار انتخابی; Malaria; P. falciparum; Tyrocidine; Selective inhibition; Cyclic peptide antibiotic; Bacillus brevis
Selective l-nitroargininylaminopyrrolidine and l-nitroargininylaminopiperidine neuronal nitric oxide synthase inhibitors
Keywords: مهار انتخابی; Neuronal nitric oxide synthase; Enzyme inhibitors; Selective inhibition; Aminopyrrolidines; Aminopiperidines
Impact of cycloheximide addition on adenylates in soil
Keywords: مهار انتخابی; ATP; ADP; AMP; Microbial biomass; Selective inhibition; Fungi; Ergosterol
Nitrogen fertilization decreases forest soil fungal and bacterial biomass in three long-term experiments
Keywords: مهار انتخابی; Nitrogen fertilization; Microbial biomass; Nitrogen saturation; Selective inhibition
Understanding the structure–activity and structure–selectivity correlation of cyclic guanine derivatives as phosphodiesterase-5 inhibitors by molecular docking, CoMFA and CoMSIA analyses
Keywords: مهار انتخابی; Phosphodiesterase; Enzyme; Inhibitor; Binding mode; Selective inhibition; Structure–activity correlation
Effects of selective tumor necrosis factor-alpha inhibition to pain-behavioral changes caused by nucleus pulposus-induced damage to the spinal nerve in rats
Keywords: مهار انتخابی; Tumor necrosis factor-alpha; Selective inhibition; Nucleus pulposus; Mechanical hyperalgesia; Thermal hyperalgesia; Spinal nerve root; Sciatica; Behavior;
Selective inhibition of divergent seryl-tRNA synthetases by serine analogues
Keywords: مهار انتخابی; aaRS, aminoacyl-tRNA synthetase; SerRS, seryl-tRNA synthetase (EC 6.1.1.11)Seryl-tRNA synthetase; Substrate analogue; Selective inhibition; Serinamide; Evolution
The adrenocortical tumor cell line NCI-H295R as an in vitro screening system for the evaluation of CYP11B2 (aldosterone synthase) and CYP11B1 (steroid-11β-hydroxylase) inhibitors
Keywords: مهار انتخابی; CYP11B2; CYP11B1; Inhibitor screening; Selective inhibition; Myocardial fibrosis; Congestive heart failure; Renin-angiotensin-aldosterone system; Adrenocortical tumor cell line NCI-H295R;