Keywords: اسپینگوماییناز; aCEase; acid-ceramidase; β-GlcCer'ase; β-glucocerebrosidase; EDTA; ethylenediaminetetraacetic acid; FLG; filaggrin; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; IL; interleukin; IVL; involucrin; LOR; loricrin; mRNA; messenger RNA; NHKs; normal hum
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Keywords: اسپینگوماییناز; bCer; brain ceramide; bSM; brain sphingomyelin; Cer; Ceramide; SM; Sphingomyelin; eggCer; egg ceramide; eggSM; egg sphingomyelin; pSM; palmitoyl sphingomyeline; pCer; palmitoyl ceramide; SMase; sphingomyelinase; Sphingomyelinase; Shear rheology; Langmuir
Assay to measure sphingomyelinase and ceramidase activities efficiently and safely
Keywords: اسپینگوماییناز; Ceramidase; Enzyme activity assay; Fluorescent substrate; Sphingomyelinase; Thin layer chromatography; High throughput;
Keywords: اسپینگوماییناز; HMG-CoA reductase; 3-hydroxy-methylglutaryl CoA reductase; Emodin; 3-methyl-1,6,8-trihydroxyanthraquinone; CL; Cardiolipin; Cer; ceramide; Ch; cholesterol; DAG; Diacylglycerol; ER; endoplasmic reticulum; EGFR; epidermal growth factor receptor; EGCG; epiga
Keywords: اسپینگوماییناز; â¢OH; hydroxyl radical; 2,2-BP; 2,2-bipyridyl; ABC; ATP-binding cassette; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; AMPKK; AMPK kinase; ANT; adenine nucleotide translocase; AP-1; activator protein 1; Apaf-1; protease activating
Ceramide binding to anandamide increases its half-life and potentiates its cytotoxicity in human neuroblastoma cells
Keywords: اسپینگوماییناز; AEA; anandamide; FAAH; fatty acid amide hydrolase; Met-AEA; methanandamide; MTS; 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium; SMase; sphingomyelinase; Endocannabinoid; Lipid domain; Cholesterol; Ceramide; Anand
Keywords: اسپینگوماییناز; BMP; bismonoacyl glycerophosphate; CE; cholesteryl ester; CHOL; cholesterol; Cer; ceramide; DAG; diacylglycerol; DRM; detergent resistant membrane; FCS; fetal calf serum; Gb3; globotriaosylceramide; GLC; gas liquid chromatography; HexCer; hexosylceramide;
Keywords: اسپینگوماییناز; Ceramide; Sphingomyelin synthase; Sphingosine kinase; Sphingomyelinase; Steatosis; Lipid droplets; TAG;
Keywords: اسپینگوماییناز; Sphingomyelin; Phospholipase D; High-throughput enzymatic assay; Improved specificity; Prevention of nonspecific reaction with lysophosphatidylcholine; SM; sphingomyelin; PC; phosphatidylcholine; LDL; low-density lipoprotein; SMase; sphingomyelinase; HPLC
Keywords: اسپینگوماییناز; 4EBP1; eukaryotic translation initiation factor 4E-binding protein 1; aCDase; acid ceramidase; Akt; Akt/protein kinase B; aSMase; acid sphingomyelinase; CalA; calyculin A; CAPP; ceramide activated protein phosphatase; CDase; ceramidase; Cer; ceramide; Des
Keywords: اسپینگوماییناز; AbA; Aureobasidin A; ABC; ATP-binding cassette; AMPK; AMP-activated protein kinase; ATG; Autophagy-related; ATP; Adenosine triphosphate; C1P; Ceramide-1-phosphate; CERS; Ceramide synthase; CK2; Casein kinase II; CLS; Chronological lifespan; CMA; Chaperone
Keywords: اسپینگوماییناز; AA; arachidonic acid; Akt (PKB); protein kinase; BMDM; bone marrow-derived macrophages; CerK; ceramide kinase; C1P; ceramide 1-phosphate; cPLA2; calcium-dependent cytosolic phospholipase 2; ERK; extracellularly regulated kinases; GLUT; glucose transporter
Keywords: اسپینگوماییناز; ACC; Acetyl-CoA carboxylase; BMP; bis(monoacylglycero)phosphate; BVDV; bovine viral diarrhea virus; CERS; ceramide synthase; CoA; Coenzyme A; COX-2; cyclooxygenase-2; DENV; dengue virus; DHCR7; 7-dehydrocholesterol reductase; dsRNA; double-stranded RNA; E
Keywords: اسپینگوماییناز; Chol; cholesterol; BODIPY; boron dipyrromethene difluoride; CDC; cholesterol-dependent cytolysins; CHO; Chinese hamster ovary; CTL; cholestatrienol; DHE; dehydroergosterol; DOPC; 1,2-dioleoyl-sn-glycero-3-phosphocholine; DPPC; 1,2-dipalmitoyl-sn-glycero-3
Keywords: اسپینگوماییناز; Plasma membrane; Repair; Resealing; Lysosome; Hydrolase; Sphingomyelinase; Protease;
Keywords: اسپینگوماییناز; Sphingomyelinase; Ceramide; Inflammation; Apoptosis; Exosomes;
Keywords: اسپینگوماییناز; 4HNE; 4-hydroxy-2-nonena 1; AA-NAT; arylalkylamine N-acetylatransferase; AFMK; N1-acetyl-N2-formyl-5-methoxykynuramine; AHr; aryl hydrocarbon receptor; AMK; N1-acetyl-5-methoxykynuramine; Apo; apolipoprotein; cAMP; cyclic adenosine monophosphate; B2-adr;
Keywords: اسپینگوماییناز; Neutrophils; Neutrophil extracellular traps; Methyl-beta-cyclodextrin; NETosis; Sphingomyelinase; NADPH-oxidases;
Keywords: اسپینگوماییناز; CPP; cell-penetrating peptide; R9; nona-arginine; Dex-(R9)5; pentavalent display of R9 on a linear dextran backbone; PI; propidium iodide; N.A.; numerical aperture; FBS; fetal bovine serum; PBS; phosphate-buffered saline; BSA; bovine serum albumin; Cell-p
Keywords: اسپینگوماییناز; Sphingomyelinase; Endoplasmic reticulum stress; Nitric oxide; Retinal pigment epithelial cells; Free radicals;
Keywords: اسپینگوماییناز; CERT; ceramide transport protein; CPE; ceramide phosphoethanolamine; ER; endoplasmic reticulum; HDL; high density lipoprotein; LCAT; lecithin:cholesterol acyltransferase; LDL; low density lipoprotein; OSBP; oxysterol binding protein; PC; phosphatidylcholi
Keywords: اسپینگوماییناز; ADR; Adriamycin-resistant; AFM; Atomic force microscopic; CTAB; Cetyltrimethylammonium bromide; DMAB; Didodecyldimethylammonium bromide; ERC; Endocytic recycling compartment; ERCC1; Excision repair cross-complementation group 1; GCS; Glucosylceramide synt
Keywords: اسپینگوماییناز; Periodate-coupled assay; Phospholipase C (PLC); Sphingomyelinase; Synthetic assay substrate; Enzyme kinetics
Sphingolipidomics analysis of large clinical cohorts. Part 2: Potential impact and applications
Keywords: اسپینگوماییناز; Sphingolipid; Lipidomics; Dementia; Stroke; Cancer; Autoimmune disease; Sphingomyelin; Ceramide; Sphingomyelinase; Sphingosine-1-phosphate; Neutral sphingomyelinase 2 (nSMase2);
Metabolomic profiling suggests long chain ceramides and sphingomyelins as a possible diagnostic biomarker of epithelial ovarian cancer
Keywords: اسپینگوماییناز; EOC; Epithelial ovarian cancer; HPLC-TQ/MS; High performance liquid chromatography-triple quadruple/mass spectrometry; AUC; area under curve; OC; ovarian cancer; BMI; body mass index; PLS-DA; partial least square discriminant analysis; VIP; variable i
Bioactive Lipid Species and Metabolic Pathways in Progression and Resolution of Nonalcoholic Steatohepatitis
Keywords: اسپینگوماییناز; Nonalcoholic Fatty Liver Disease; Triglycerides; Fatty Acids; Therapy; AA; arachidonic acid; ACC; acetyl-coenzyme A carboxylase; ASMase; acid sphingomyelinase; CeS; ceramide synthase; CoA; coenzyme A; COX; cyclo-oxygenase; DES; dihydro-ceramide desatura
The Hog1p kinase regulates Aft1p transcription factor to control iron accumulation
Keywords: اسپینگوماییناز; BPS; bathophenanthrolinedisulfonate; GST; glutathione S-transferase; PDS; post-diauxic-shift; TORC1; target of rapamycin complex 1; V-ATPase; vacuolar H+-ATPase; YPD; yeast extract peptone dextrose; Iron; Sphingomyelinase; Isc1p; Aft1p; Hog1p; Cell signal
Caveolae-mediated effects of TNF-α on human skeletal muscle cells
Keywords: اسپینگوماییناز; Caveolae; Myoblasts; Inflammation; TNF-α; Oxidative stress; Sphingomyelinase;
Discovery of the selective sphingomyelin synthase 2 inhibitors with the novel structure of oxazolopyridine
Keywords: اسپینگوماییناز; SMS; sphingomyelin synthase; SM; sphingomyelin; PC; phosphatidylcholine; CHD; coronary heart disease; SMase; sphingomyelinase; SPT; serine palmitoyl transferase; AS; atherosclerosis; SMSr; SMS related protein; SAR; structure-activity relationships; IC50;
Modulation of the sphingolipid rheostat is involved in paclitaxel resistance of the human prostate cancer cell line PC3-PR
Keywords: اسپینگوماییناز; Paclitaxel resistance; Human prostate cancer cell line; SPHK1; Glucosylceramide synthase; Sphingomyelinase; Sphingolipid rheostat; ACDase; acid ceramidase; ASMase; acid sphingomyelinase; DNR; daunorubicin; GCS; glucosylceramide synthase; LC-MS/MS; liquid
Sphingolipids and glycerophospholipids - The “ying and yang” of lipotoxicity in metabolic diseases
Keywords: اسپینگوماییناز; AA; arachidonic acid; AKT; RAC-alpha serine/threonine-protein kinase; CCTα; choline-phosphate cytidylyltransferase A; CERK; Ceramide Kinase; C1P; ceramide-1-phosphate; CerS; ceramide synthase; CERT; ceramide transport protein; HDL; high-density lipoprote
Dual signaling evoked by oxidized LDLs in vascular cells
Keywords: اسپینگوماییناز; AAPH; 2,2'-azobis(2-amidinopropane) dihydrochloride; AIF; apoptotic inducing factor; AMVN; 2,4-dimethylvaleronitrile; AP-1; activator protein 1; ATF6; activating transcription factor 6; CDE; clathrin-dependent endocytosis; CCL2; chemokine ligand 2 (or MCP
Lipidomic profile of GM95 cell death induced by Clostridium perfringens alpha-toxin
Keywords: اسپینگوماییناز; AC; acyl carnitine; ATX; alpha-toxin; Cer; ceramide; ChoE; cholesteryl esters; DAG; diacylglycerol; DGAT; Diglyceride acyltransferase; GPL; glycerophospholipids; LPC; ,lysophosphatidylcholine; LPE; lysophosphatidylethanolamine; LPI; lysophosphatidylinosit
An acidic sphingomyelinase Type C activity from Mycobacterium tuberculosis
Keywords: اسپینگوماییناز; Mycobacterium tuberculosis; Tuberculosis; Sphingomyelinase; Virulence factors; MexicoMycobacterium tuberculosis; Tuberculosis; Esfingomielinasa; Factores de virulencia; México
Vitamin E metabolite 13â²-carboxychromanols inhibit pro-inflammatory enzymes, induce apoptosis and autophagy in human cancer cells by modulating sphingolipids and suppress colon tumor development in mice
Keywords: اسپینگوماییناز; 13â²-COOH; 13â²-carboxychromanol; αT, γT, or δT; α, γ, or δ-tocopherol; γTE or δTE; γ, δ-tocotrienol; δT-13'-COOH or δT-13â²; 13â²-COOH derived from δT; δTE-13â²-COOH or δTE-13â²; 13â²-COOH derived from δTE; COX; cyclooxygenase; 5
Cross talk between MMP2-Spm-Cer-S1P and ERK1/2 in proliferation of pulmonary artery smooth muscle cells under angiotensin II stimulation
Keywords: اسپینگوماییناز; ANG II; NADPH oxidase; proMMP-2; S1P; Cell proliferation; BPASMC; SMC; smooth muscle cell; ANG II; angiotensin II; AT1R; angiotensin receptor type-1; AT2R; angiotensin receptor type-2; proMMP-2; pro matrix metalloprotease-2; SMase; sphingomyelinase; SPHK;
Regulation of ceramide generation during macrophage apoptosis by ASMase and de novo synthesis
Keywords: اسپینگوماییناز; ASMase; acid sphingomyelinase; BMDMs; bone marrow-derived macrophages; C1P; ceramide 1-phosphate; M-CSF; macrophage colony stimulating factor; MTS; [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulphophenyl)-2H-tetrazolium, inner salt]; SP
Sphingomyelin derivatives increase the frequency of microvesicle and granule fusion in chromaffin cells
Keywords: اسپینگوماییناز; AA; arachidonic acid; DMEM; Dulbecco's modified Eagle's medium; FCS; fetal calf serum; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; MSD; Mean Square Displacement; SMase; sphingomyelinase; SNAP-25; synaptosomal-associated protein of 25Â K
Induction of eryptosis by low concentrations of E. coli alpha-hemolysin
Keywords: اسپینگوماییناز; HlyA; alpha hemolysin; PS; phosphatidylserine; SMase; sphingomyelinase; PC; phosphatidylcholine; SM; sphingomyelin; RTX toxin; Eryptosis; μ-Calpains; Endogenous sphingomyelinase; Cytoskeleton;
Critical determinants of mitochondria-associated neutral sphingomyelinase (MA-nSMase) for mitochondrial localization
Keywords: اسپینگوماییناز; SMase; sphingomyelinase; N-SMase; neutral sphingomyelinase; SMPD; sphingomyelin phosphodiesterase; SM; sphingomyelin; MAMS; mitochondria-associated membranes; CerS; ceramide synthase; Hsp; heat shock protein; MLS; mitochondrial localization signal; TMD; t
à propos d'un cas de maladie de Niemann-Pick type C : revue de la littérature
Keywords: اسپینگوماییناز; Cholestérol; maladie de Niemann-Pick; surcharge; sphingolipides; sphingomyélinase; Cholesterol; Niemann-Pick diseases; storage; sphingolipids; sphingomyeliase;
Oncogenic ras-driven cancer cell vesiculation leads to emission of double-stranded DNA capable of interacting with target cells
Keywords: اسپینگوماییناز; Extracellular vesicle; DNA; Oncogene; Ras; Chromatin; Sphingomyelinase;
Involvement of diacylglycerol produced by phospholipase D activation in Aβ-induced reduction of sAPPα secretion in SH-SY5Y neuroblastoma cells
Keywords: اسپینگوماییناز; Alzheimer disease; Amyloid β; Phospholipase D; Diacylglycerol; Ceramide; Sphingomyelinase;
Development of a homogeneous assay for measurement of high-density lipoprotein-subclass cholesterol
Keywords: اسپینگوماییناز; TRLs; TG rich lipoproteins; HLB; hydrophilic lipophilic balance; SMase; sphingomyelinase; Hep-Mn; heparin-manganese; DS; dextran sulfate; TOOS; N-Ethyl-N-(2-hydroxy-3-sulfopropyl)-3-methylaniline, sodium salt, dehydrate; BES; N,N-Bis(2-hydroxyethyl)-2
Trk receptors need neutral sphingomyelinase activity to promote cell viability
Keywords: اسپینگوماییناز; BDNF; Brain-Derived Neurotrophic Factor; Cer; ceramide; CGN; cultured granule neurons; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NGF; Nerve Growth Factor; nSMase; neutral sphingomyelinase; NT; neurotrophins; SM; sphingomyelin; Sph
Lipid bilayers containing sphingomyelins and ceramides of varying N-acyl lengths: A glimpse into sphingolipid complexity
Keywords: اسپینگوماییناز; Sphingomyelin; Ceramide; Differential scanning calorimetry; Atomic force microscopy; Sphingomyelinase; Interdigitation;
Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells
Keywords: اسپینگوماییناز; SRSF1; serine/arginine-rich splicing factor 1; PP1; protein phosphatase 1; GCS; glucosylceramide synthase; MBO-asGCS; mixed backbone oligonucleotide against glucosylceramide synthase; PDMP; d-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol; SMase;
Exoproteome analysis of a novel strain of Bacillus cereus implicated in disease resembling cutaneous anthrax
Keywords: اسپینگوماییناز; Bacillus cereus; Cutaneous anthrax; S-layer protein; Sphingomyelinase;
Bacillus cereus sphingomyelinase recognizes ganglioside GM3
Keywords: اسپینگوماییناز; B. cereus; Bacillus cereus; SMase; sphingomyelinase; Bc-SMase; Bacillus cereus sphingomyelinase; GM3; NeuAcα2-3Galβ1-4Glcβ1-1ceramide; SPR; surface plasmon resonance; Bacillus cereus; Sphingomyelinase; GM3; β-Hairpin; Tethering;
HDL drug carriers for targeted therapy
Keywords: اسپینگوماییناز; HDL; high-density lipoprotein; SR-BI; scavenger receptor class B type I; eNOS; endothelial nitric oxide synthase; miRNAs; microRNAs; S1PRs; sphingosine 1-phosphate receptors; S1P; sphingosine 1-phosphate; PGI2; prostaglandin I2; COX-2; cyclooxygenase-2; F