Keywords: استریچنینی; Horizontal natural products transfer; Contamination; Alkaloids; Berberine; Pyrrolizidine alkaloids; Strychnine; ACN; acetonitrile; HPLC; high performance liquid chromatography; MeOH; methanol; PAs; pyrrolizidine alkaloids; TFA; trifluoroacetic acid; UV; u
مقالات ISI استریچنینی (ترجمه نشده)
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Keywords: استریچنینی; Glycine receptor; Strychnine; Medial prefrontal cortex
Keywords: استریچنینی; Strychnine; Proton-transfer; Nanoporous carbon; SEM; TEM;
Keywords: استریچنینی; Naftopidil; Noradrenaline; Strychnine; Bicuculline; Micturition reflex
Keywords: استریچنینی; Ionic liquid; Electromembrane extraction; Strychnine; Brucine; Human urine
Keywords: استریچنینی; Density functional theory; Brucine; Strychnine; Molecular electrostatic potential; Hyperpolarizability;
Keywords: استریچنینی; AC/AE; anticonvulsant/antiepileptic; CNS; central nervous system; FL; fidelity level; Gr; grass; H; herb; MES; maximal electro-shock; NA; information not available; PILO; pilocarpine; PTZ; pentylenetetrazole; S; shrub; STR; strychnine; Tr; tree; UV; use v
Microdialysis combined with RRLC-MS/MS for the pharmacokinetics of two major alkaloids of Bi qi capsule and the potential roles of P-gp and BCRP on their penetration
Keywords: استریچنینی; BQC; Bi qi capsule; BBB; blood-brain barrier; RRLC-MS/MS; rapid resolution liquid chromatography -tandem mass spectrometry; P-gp; P-glycoprotein; BCRP; breast cancer resistance protein; CNS; central nervous system; CSF; cerebrospinal fluid; LLOQ; lower li
Removal of hERG potassium channel affinity through introduction of an oxygen atom: Molecular insights from structure-activity relationships of strychnine and its analogs
Keywords: استریچنینی; hERG channel; Strychnine; Brucine; N-oxide; Alanine-mutagenesis; Docking simulations;
Anticonvulsant evaluation of novel non-imidazole histamine H3R antagonists in different convulsion models in rats
Keywords: استریچنینی; Histamine H3 receptors; Antagonists; Anticonvulsant; Maximal electroshock; Pentylenetetrazole; Strychnine; Antiproliferative action; Genotoxicity assessment;
Enhanced cleanup efficiency hydroxy functionalized-magnetic graphene oxide and its comparison with magnetic carboxyl-graphene for PRiME pass-through cleanup of strychnine and brucine in human plasma samples
Keywords: استریچنینی; Enhanced cleanup efficiency hydroxy functionalized-magnetic graphene oxide (EH-Mag-GO); PRiME (process, robustness, improvements, matrix effects, ease of use) pass-through cleanup; Liquid chromatography-tandem quadrupole mass spectrometry (LC-MS/MS); Stry
Orexin-B modulates synaptic transmission of rod bipolar cells in rat retina
Keywords: استریچنینی; Orexin; Retinal rod bipolar cell; GABA receptor; Neuromodulation; BCs; bipolar cells; BIC; bicuculline; Bis-IV; bisindolylmaleimide IV; CPPG; (RS)-α-cyclopropyl-4-phosphor- nophenylalycine; DAG; diacylglycerol; DLG; dorsal lateral geniculate nucleus; DT-
Phenylalanine derivatives with modulating effects on human α1-glycine receptors and anticonvulsant activity in strychnine-induced seizure model in male adult rats
Keywords: استریچنینی; ANOVA; analysis of variance; BAPTA; 1,2-bis(o-aminophenoxy)ethane-N,N,N9,N9-tetraacetic acid; DA; dopamine; DMSO; dimethylsulfoxide; MBS; Barth's solution; nAChR; nicotinic acetylcholine receptor; α1-GLYRs; α1-glycine receptor; ROS; radical oxygen spe
LC–MS/MS determination and comparative pharmacokinetics of strychnine, brucine and their metabolites in rat plasma after intragastric administration of each monomer and the total alkaloids from Semen Strychni
Keywords: استریچنینی; Strychnine; Brucine; Strychnine N-oxide; Brucine N-oxide; LC–MS/MS; Pharmacokinetics; The total strychnos alkaloids; Monomer; Rat plasma
Structural and chiroptical analysis of naturally occurring (–)-strychnine
Keywords: استریچنینی; Strychnine; Structure; NMR; Optical rotation; Electronic circular dichroism; Conformation
Anticonvulsant and procognitive properties of the non-imidazole histamine H3 receptor antagonist DL77 in male adult rats
Keywords: استریچنینی; Histamine H3 receptor; Epilepsy; Anticonvulsant; Learning; Memory; Passive avoidance test; Pyrilamine; R-(α)-methyl-histamine; H3Rs; histamine H3 receptors; MES; maximal electroshock; PTZ; pentylenetetrazole; STR; strychnine; AED; antiepileptic drug; PHT
Artifacts in time-resolved NUS: A case study of NOE build-up curves from 2D NOESY
Keywords: استریچنینی; Time-resolved spectroscopy; Non-uniform sampling; NOESY; Signal-to-artifact ratio; Variable mixing time; Strychnine;
Anticonvulsant effects of ethanol stem bark extract of Lannea barteri (Anacardiaceae) in mice and chicks
Keywords: استریچنینی; Lannea barteri; Epilepsy; Maximal electroshock; Pentylenetetrazole; Strychnine; Picrotoxin;
Glycine plays a crucial role as a co-agonist of NMDA receptors in the neuronal circuit generating body movements in rat fetuses
Keywords: استریچنینی; Strychnine; NMDA receptor glycine binding site; Fetal movement; Brainstem-spinal cord preparation;
Conformational analysis of small organic molecules using NOE and RDC data: A discussion of strychnine and α-methylene-γ-butyrolactone
Keywords: استریچنینی; Nuclear Overhauser Effect; Residual Dipolar Couplings; Configuration determination; Conformational analysis; Strychnine;
Broadband inversion of 1JCC responses in 1,n-ADEQUATE spectra
Keywords: استریچنینی; 1,n-ADEQUATE; 1,1-ADEQUATE; Pulse sequence; Broadband inversion; Strychnine;
Gelsemine, a principal alkaloid from Gelsemium sempervirens Ait., exhibits potent and specific antinociception in chronic pain by acting at spinal α3 glycine receptors
Keywords: استریچنینی; Gelsemine; Chronic pain; Glycine receptor; Spinal cord; Strychnine; GlyR α3 subunit;
Anticonvulsant action of Calotropis procera latex proteins
Keywords: استریچنینی; Calotropis procera; Strychnine; Pilocarpine; Sleeping time; Anticonvulsant effect; Apocynaceae
Chemical conversion of strychnine into kopsiyunnanine-I, a new hexacyclic indole alkaloid from Yunnan Kopsia arborea
Keywords: استریچنینی; Kopsia arborea; Indole alkaloid; Kopsiyunnanine-I; Strychnine;
Anticonvulsant effects of agomelatine in mice
Keywords: استریچنینی; Agomelatine; Strychnine; Pilocarpine; Electroshock stimulation; Anticonvulsant effect; Picrotoxin; Seizure; Melatonin
Brief embryonic strychnine exposure in zebrafish causes long-term adult behavioral impairment with indications of embryonic synaptic changes
Keywords: استریچنینی; Zebrafish; Development; Strychnine; Synaptic; Behavior; Novel Tank Diving Task;
Antiepileptic activity of lobeline isolated from the leaf of Lobelia nicotianaefolia and its effect on brain GABA level in mice
Keywords: استریچنینی; Lobelia nicotianaefolia; Lobeline; Brain GABA level; Antiepileptic activity; Pentylenetetrazol (PTZ); Strychnine;
Analgesic and anti-inflammatory activity and pharmacokinetics of alkaloids from seeds of Strychnos nux-vomica after transdermal administration: Effect of changes in alkaloid composition
Keywords: استریچنینی; Strychnos nux-vomica L.; Brucine; Strychnine; Analgesic; Anti-inflammatory; Transdermal;
Effects of Ignatia amara in mouse behavioural models
Keywords: استریچنینی; Strychnos Ignatii; Ignatia; Strychnine; Animal models of anxiety; Open-Field test; Light–Dark test; Homeopathic dilutions/dynamizations; Nanopharmacology
Determination of strychnine and brucine in traditional Chinese medicine preparations by capillary zone electrophoresis with micelle to solvent stacking
Keywords: استریچنینی; On-line sample preconcentration; Micelle to solvent stacking; Capillary zone electrophoresis; Strychnine; Brucine; Traditional Chinese medicine preparation
Ultra-performance liquid chromatography–tandem mass spectrometric method for the determination of strychnine and brucine in mice plasma
Keywords: استریچنینی; Semen Strychni; Strychnine; Brucine; UPLC–MS/MS
Research ReportGlycine-activated chloride currents of neurons freshly isolated from the prefrontal cortex of young rats
Keywords: استریچنینی; Whole cell patch-clamp; Prefrontal cortex; Glycine receptor; Strychnine; Picrotoxin;
Modulation of endocannabinoid-mediated long-lasting disinhibition of striatal output by cholinergic interneurons
Keywords: استریچنینی; Basal ganglia; Cannabinoid 1 receptor; Mecamylamine; Strychnine; Synaptic plasticity;
Inhibition of human Nav1.5 sodium channels by strychnine and its analogs
Keywords: استریچنینی; Nav1.5 channel; Alkaloid; Strychnine; Icajine; Arrhythmias
Glycine inhibits startle-mediating neurons in the caudal pontine reticular formation but is not involved in synaptic depression underlying short-term habituation of startle
Keywords: استریچنینی; Startle; Habituation; Caudal pontine reticular formation; Synaptic depression; Glycine; Strychnine; Inhibition; Rat
Respiratory responses induced by blockades of GABA and glycine receptors within the Bötzinger complex and the pre-Bötzinger complex of the rabbit
Keywords: استریچنینی; BötC; Bötzinger complex; preBötC; pre-Bötzinger complex; PRG; pontine respiratory group; TE; expiratory time; TI; inspiratory time; VRC; ventral respiratory column; Inhibitory amino acid receptor; Control of respiration; Respiratory rhythm generation;
Design and synthesis of 5-alkoxy-[1,2,4]triazolo[4,3-a]quinoline derivatives with anticonvulsant activity
Keywords: استریچنینی; 1,2,4-Triazolo[4,3-a]quinoline; Triazole; Quinoline; Anticonvulsant; Maximal electroshock; Neurotoxicity; Pentylenetetrazole; Isoniazid; Thiosemicarbazide; 3-Mercaptopropionic acid; Strychnine
Determination of strychnine and brucine in rat plasma using liquid chromatography electrospray ionization mass spectrometry
Keywords: استریچنینی; Strychnine; Brucine; Semen Strychni; LC–ESI-MS; Rat plasma
Design, synthesis of 8-alkoxy-5,6-dihydro-[1,2,4]triazino[4,3-a]quinolin-1-ones with anticonvulsant activity
Keywords: استریچنینی; 1,2,4-Triazino[4,3-a]quinolin-1-one; Triazone; Anticonvulsant; MES; Pentylenetetrazole; Isoniazid; Thiosemicarbazide; 3-Mercaptopropionic acid; Strychnine
Intracerebroventricular or intrathecal injection of glycine produces analgesia in thermal nociception and chemical nociception via glycine receptors
Keywords: استریچنینی; Glycine; Glycine receptor; Analgesia; Strychnine;
Characterization of the anticonvulsant activity of doxepin in various experimental seizure models in mice
Keywords: استریچنینی; doxepin; maximal electroshock; rotarod test; pentylenetetrazole; 3-mercaptopropionic acid; bicuculline; thiosemicarbazide; strychnine
Effects of the β-amino acid antagonist TAG on thalamocortical inhibition
Keywords: استریچنینی; TAG; Glycine receptor; GABAA receptor; IPSC; Strychnine; Thalamus
l-Serine induces sedative and hypnotic effects acting at GABAA receptors in neonatal chicks
Keywords: استریچنینی; L-Serine; GABAA receptor; Glycine receptor; Picrotoxin; Strychnine; Chick
Methodological optimization of applying neuroactive agents for the study of locomotor-like activity in the mudpuppies (Necturus maculatus)
Keywords: استریچنینی; Drug application; Locomotion; Central pattern generator; Spinal cord; Mudpuppy; NMDA; Glutamate; Strychnine; DMSO; Neuromodulation;
Phythochemical screening and anticonvulsant activity of Cymbopogon winterianus Jowitt (Poaceae) leaf essential oil in rodents
Keywords: استریچنینی; Cymbopogon winterianus; CNS depressant; Anticonvulsant activity; Pentylenetetrazol; Picrotoxin; Strychnine
Newer GABA derivatives for the treatment of epilepsy including febrile seizures: A bioisosteric approach
Keywords: استریچنینی; Thiosemicarbazones; Anticonvulsants; GABA; Pentylenetetrazole; Picrotoxin; Strychnine; Febrile seizures
Synthesis of novel 7-benzylamino-2H-1,4-benzoxazin-3(4H)-ones as anticonvulsant agents
Keywords: استریچنینی; 1,4-Benzoxazin-3(4H)-one; Anticonvulsant; MES; sc-PTZ; Isoniazid; Strychnine
New technique for drug application to the spinal cord of walking mice
Keywords: استریچنینی; Mice; Walking; Drug application; Spinal cord; Strychnine; Buprenorphine
Spatiotemporal organization of frog respiratory neurons visualized on the ventral medullary surface
Keywords: استریچنینی; Control of breathing; Brainstem; Respiratory neurons; Oscillators; Evolution of breathing; Frog; Buccal ventilation; Lung ventilation; Voltage imaging; Cross-correlation; Strychnine; Reciprocal inhibitory networks
Glycine-mediated changes of onset reliability at a mammalian central synapse
Keywords: استریچنینی; strychnine; synaptic transmission; spike timing; calyx of Held; MNTB; in vivo physiologyAChR, acetylcholine receptor; ACSF, artificial cerebrospinal fluid; AVCN, anteroventral cochlear nucleus; CF, characteristic frequency; [Cl−]i, intracellular chloride