Feasibility and Efficacy of a Mass Switch from Latanoprost to Bimatoprost in Glaucoma Patients in a Prepaid Health Maintenance Organization

A systematic pharmacy-level switch from latanoprost to bimatoprost in a nationwide HMO achieved a high switch rate, with little switching back. There was a small but statistically significant reduction in mean IOP after the switch. An appreciable proportion of patients switched had a clinically significant reduction of IOP.