| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10008737 | Annals of Allergy, Asthma & Immunology | 2005 | 7 Pages |
Abstract
We observed differential FK506 sensitivity of IL-15-driven CD25 up-regulation and apoptotic response comparing CB and APB T cells. This finding suggests the potential therapeutic benefit of FK506 in ameliorating graft-vs-host disease by decreasing IL-15-driven donor T-cell proliferation without inhibiting associated activation-induced apoptosis during CB transplantation.
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Authors
Syh-Jae MD, Dah-Chin MD, Ming-Ling PhD, Po-Jen MD, Shiu-Shan BS, Tien-Lung PhD,