Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10030663 | Transactions of the Royal Society of Tropical Medicine and Hygiene | 2005 | 4 Pages |
Abstract
Tafenoquine is an 8-aminoquiniline related to primaquine with pre-clinical activity against a range of malaria species. We treated two acute cases of vivax malaria with tafenoquine (800Â mg over three days) alone, instead of conventional chloroquine (1500Â mg over three days) and primaquine (420Â mg over 14 days). In addition to the convenience of this regimen, the rapid parasite clearances observed, coupled with a good clinical response and lack of recrudescence or relapse, indicate that further investigation of tafenoquine in the treatment of vivax malaria is warranted.
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Authors
Peter Nasveld, Scott Kitchener,