Article ID Journal Published Year Pages File Type
10032598 American Journal of Obstetrics and Gynecology 2005 7 Pages PDF
Abstract
Opposing changes in drug metabolism occur during pregnancy, with CYP1A2 activity decreased and CYP2D6 and CYP3A activities increased. The direction of dosing adjustments during pregnancy will depend on the drug and the enzyme that is responsible for its metabolism.
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Related Topics
Health Sciences Medicine and Dentistry Medicine and Dentistry (General)
Preview
Temporal changes in drug metabolism (CYP1A2, CYP2D6 and CYP3A Activity) during pregnancy
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