Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10032641 | American Journal of Obstetrics and Gynecology | 2005 | 5 Pages |
Abstract
The overall distribution of midtrimester amniotic fluid matrix metalloproteinase-8 levels did not differ between women who had preterm premature rupture of membranes and those delivered at term. However, marked elevations of midtrimester amniotic fluid matrix metalloproteinase-8 were highly associated with subsequent preterm premature rupture of membranes, suggesting that the pathophysiologic processes that contribute to preterm premature rupture of membranes may begin in early pregnancy.
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Authors
Joseph R. MD, Patrick S. MD, Suzanne P. Cliver, Martha D. Lyon, Robert L. MD, Katharine D. MD,