Reduction in Induced Pain by Ultrasound May Be Caused by Altered Expression of Spinal Neuronal Nitric Oxide Synthase-Producing Neurons

US treatment may modulate the CFA insult-induced increase in total and regional nNOS-LI neurons. I propose that the peripheral influences of US on central modulation of the spinal nociceptive processing system is important and may reflect the neuroplasticity of the spinal cord in response to peripheral input.