| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10041471 | Archives of Physical Medicine and Rehabilitation | 2005 | 4 Pages |
Abstract
Pruritus is a frequent symptom after ITB withdrawal. Its occurrence is probably subsequent to chronic blocking of the liberation of substance P by baclofen at the spinal level. This symptom is a good clinical predictor of baclofen withdrawal, in contrast to an isolated increase of spasticity that may be due to drug tolerance or irritant factors. Pruritus requires investigation of a possible dysfunction of the infusion system.
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Authors
Djamel MD, Caroline MD, Pierre MD, Bernard MD,