| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10051881 | The Journal of Urology | 2005 | 4 Pages |
Abstract
Serum α-tocopherol is increased by oral supplementation of vitamin E. We found that α-tocopherol supplementation has no effect on serum androgens, IGF-1 or PSA. The lack of an effect of vitamin supplementation on PSA avoids any bias in the diagnosis of prostate cancer in vitamin E treated patients. Our results suggest that a decrease in prostate cancer risk with α-tocopherol is likely to occur through a mechanism that is nonhormonal and independent of IGF-1.
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Authors
JAVIER HERNÁANDEZ, SAMIRA SYED, GEOFFREY WEISS, GABRIEL FERNANDES, DENDRA von MERVELDT, DEAN A. TROYER, JOSEPH W. BASLER, IAN M. JR,