Article ID Journal Published Year Pages File Type
10052046 The Journal of Urology 2005 4 Pages PDF
Abstract
Loss of E-cadherin expression correlates with loss of intercellular adhesion, tight junction formation and enhanced paracellular transport. The data show that E-cadherin hampers the permeation of hypericin in spheroids and the loss of intercellular adhesion, present in superficial bladder cancer lesions, can be associated with enhanced hypericin permeation. Therefore, E-cadherin expression seems to have a pivotal role in the selective uptake of hypericin after intravesical instillation in human bladders.
Related Topics
Health Sciences Medicine and Dentistry Nephrology
Authors
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