Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10052554 | The Journal of Urology | 2005 | 6 Pages |
Abstract
Analysis of the primary efficacy outcome did not reveal a statistically significant effect of treatment. However, secondary analyses demonstrated that tolterodine was well tolerated among 5 to 10-year-old children with diurnal incontinence. Exploratory analyses also showed that children weighing 35 kg or less with detrusor overactivity characterized by incontinence and/or frequent voiding benefited most from tolterodine treatment, suggesting that a weight adjusted dosing regimen may be required for optimal response among older and heavier children.
Related Topics
Health Sciences
Medicine and Dentistry
Nephrology
Authors
RIEN J.M. NIJMAN, NIELS G. BORGSTEIN, PAMELA ELLSWORTH, JENS C. DJURHUUS,