| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10064534 | European Journal of Obstetrics & Gynecology and Reproductive Biology | 2005 | 5 Pages |
Abstract
Our study shows for the first time that the pro-apoptotic proteins BNip3 and Nix are expressed in the human placenta. Pregnancies with placental dysfunction and hypertensive pregnancy disorders with different clinical manifestations are characterized by a significantly decreased expression of BNip3 and Nix. These results suggest that the hypothesis of generally increased placental apoptosis in pregnancy-induced hypertensive disorders caused by disturbed trophoblast invasion has to be partly reconsidered.
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Authors
H. Stepan, C. Leo, S. Purz, M. Höckel, L.-C. Horn,