Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10064609 | European Journal of Obstetrics & Gynecology and Reproductive Biology | 2005 | 5 Pages |
Abstract
In adolescent girls who are anovulatory and moderately obese, metformin administration can have a normalizing effect on multiple aberrations within the endocrine-metabolic status. During the reproductive period, metformin administration can improve reproductive function and the establishment of pregnancy. A role of metformin in prevention of gestational diabetes and hypertensive complications of pregnancy has yet to be shown. Finally, any real benefit of insulin-lowering treatment in terms of lesser cardiovascular risk in women with PCOS women remains to be demonstrated.
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Authors
Antonio La Marca, Alfredo Carducci Artensio, Gaspare Stabile, Annibale Volpe,