Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10064684 | European Journal of Obstetrics & Gynecology and Reproductive Biology | 2005 | 8 Pages |
Abstract
Different patterns of chromosomal aberrations are seen in precursor lesions than in endometrial carcinomas, except for the loss of 1p36-pter. The presence of 1p deletion in both endometrial hyperplasia and cancer specimens suggests that this is an early event in the development of carcinoma. These results support a stepwise mode of tumorigenesis with accumulation of a series of genomic copy alterations in endometrial carcinogenesis.
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Authors
Hamza M. Muslumanoglu, U. Oner, S. Ozalp, M.F. Acikalin, O.T. Yalcin, M. Ozdemir, S. Artan,