| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10070362 | Taiwanese Journal of Obstetrics and Gynecology | 2005 | 5 Pages |
Abstract
PNETs belong to the Ewing's sarcoma family. They are closely related to malignant, small round-cell tumors of soft tissue and bones. They strongly express the glycoprotein p30/32 (CD99) on the cell membrane, which is encoded by the MIC2 gene. A translocation at t(11;22)(q24;q12) has been identified. PNETs are mostly recognized by the histologic characteristics of neural differentiation and immunohistochemical expression of at least two different neural markers. Uterine PNETs have a poor prognosis and, to date, there is no standard treatment. Total abdominal hysterectomy and bilateral salpingo-oophorectomy plus adjuvant chemotherapy or radiotherapy are recommended.
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Authors
Tzu-Chen Yeh, Kian-Mei Chong, Yu-Hung Lin, Hun-Shan Pan, Kok-Min Seow, Jiann-Loung Hwang, Lee-Wen Huang,