Article ID Journal Published Year Pages File Type
10070566 European Journal of Surgical Oncology (EJSO) 2005 6 Pages PDF
Abstract
Coding region mutation in TP53 occurs in 25% of ACCs with a trend toward a poorer prognosis. Promoter methylation of TP53 is not present in ACC as a mechanism for tumour suppressor gene (TSG) inactivation and, therefore, other genes in the 17p13 region are implicated in adrenal carcinogenesis.
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Authors
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