Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10070566 | European Journal of Surgical Oncology (EJSO) | 2005 | 6 Pages |
Abstract
Coding region mutation in TP53 occurs in 25% of ACCs with a trend toward a poorer prognosis. Promoter methylation of TP53 is not present in ACC as a mechanism for tumour suppressor gene (TSG) inactivation and, therefore, other genes in the 17p13 region are implicated in adrenal carcinogenesis.
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Authors
S. Sidhu, E. Martin, C. Gicquel, J. Melki, S.J. Clark, P. Campbell, C.J. Magarey, K.M. Schulte, H.D. Röher, L. Delbridge, B.G. Robinson,