Use of Progressive Glaucomatous Optic Disk Change as the Reference Standard for Evaluation of Diagnostic Tests in Glaucoma

SLP differentiated patients with documented progressive optic disk change from normal subjects and detected abnormalities in patients with confirmed diagnosis of preperimetric GON, suggesting that it may be useful for early glaucoma diagnosis. We suggest that progressive optic disk change should be used in the evaluation of diagnostic accuracy of imaging instruments for glaucoma.