Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10083186 | The Journal of Hand Surgery | 2005 | 7 Pages |
Abstract
Delivery of exogenous bFGF gene to tenocytes can increase significantly the levels of expression of the bFGF and type I and III collagen genes. AAV2 vectors provide a novel method for delivering growth factor genes to tenocytes. These findings warrant future in vivo study of the delivery of genes pertinent to tendon healing through AAV2-based gene therapy to enhance repairs of injured flexor tendons.
Related Topics
Health Sciences
Medicine and Dentistry
Orthopedics, Sports Medicine and Rehabilitation
Authors
Xiao Tian MD, Paul Y. MD, Ke-Qin MD, PhD, Jin Bo MD,