| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10087215 | British Journal of Plastic Surgery | 2005 | 7 Pages |
Abstract
Local administration of morphine in higher doses (1 and 5 mg/flap) significantly reduced the amount of flap necrosis when compared to that of the control cohort (P<0.05). Naloxone abolished this protective effect of morphine. Furthermore naloxone significantly decreased the anti-ischaemic effect of the IPC. Systemic administrations of morphine had no significant effect on flap survival area in compare with the control group.
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Authors
S. Kiumehr, S. Demehri, S. Rabbani, S. Amanpour, M.A. Mohagheghi, A.R. Dehpour,