Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10090548 | Annals of Diagnostic Pathology | 2005 | 4 Pages |
Abstract
Although primary melanomas show a higher level of cyclin D1 expression compared with nevi, cyclin D1 appears to have little role in development of a metastatic phenotype. It is not clear why lesions localized near the dermal-epidermal junction express higher levels of cyclin D1. Further studies are indicated to ascertain the biologic role and practical utility of cyclin D1 in melanocytic lesions of the skin.
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Authors
James A. MD, Joan MD, M. Sambasiva MD, Leslie K. MD,