Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10091456 | The Journal of Pediatrics | 2005 | 5 Pages |
Abstract
In newborns with IUGR, the changes in measured plasma free fraction of L-Trp and in the amplitude the N1/P2 component of the AEP suggest an inverse association between free L-Trp and components of the AEP. The changes observed in the free fraction of L-Trp and AEP may be causally associated with brain serotonergic activity in utero. In IUGR, epigenetic factors such as stress-induced disturbances in brain serotonin metabolism or serotonergic activity, identifiable by alterations in AEP, influence cerebral sensory cortex development and may be causally associated with serotonin-related disorders in adulthood.
Keywords
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Authors
Gabriel MD, PhD, Ignacia MD, Rocio MD, MSc, Felipe MD, MSc, Alejandro Robles, Jorge MD, PhD,