Article ID Journal Published Year Pages File Type
10101308 The American Journal of Surgery 2005 5 Pages PDF
Abstract
TIMP-1 manipulation, particularly underexpression, greatly reduces the invasive potential of pancreatic cancer by limiting MMP-2 activity without affecting in vitro cell growth. TIMP-1 is a reasonable molecular target in pancreatic cancer therapy.
Keywords
Related Topics
Health Sciences Medicine and Dentistry Surgery
Preview
TIMP-1 antisense gene transfection attenuates the invasive potential of pancreatic cancer cells in vitro and inhibits tumor growth in vivo
Authors
, , , ,