| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10106293 | Journal of Surgical Research | 2019 | 10 Pages |
Abstract
This study demonstrated that the expression of Shh, Ptch1, and Gli1 in lumbosacral spinal cord was remarkably reduced during late developmental stages in fetal rats with ARMs. These findings offered some important insights into the involvement of the Shh-Ptch1-Gli1 signaling pathway in the pathogenesis of lumbosacral spinal cord maldevelopment in rat fetus with ARMs, which leads to complications after procedures for ARMs.
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Authors
Zhonghua PhD, MD, Linlin Gao, Huimin PhD, MD, Yuzuo PhD, MD, Weilin PhD, MD,