| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10106899 | IBRO Reports | 2018 | 31 Pages |
Abstract
Ccdc66 -/- mice develop substantial olfactory nerve fiber degeneration and alteration of olfaction-related behavior at advanced age. Thus, the Ccdc66 -/- mouse model for retinal degeneration adds the possibility to study mechanisms of central nervous system degeneration.
Keywords
CTXGPRAONFSEZperiglomerular cellsRetinitis pigmentosaAstrogliaSVZPBSORNONLIPLEPLRIPAIODGAPDHMOBRMSolfactory epitheliumNeurodegenerationrostral migratory streamDendritepostnatal daysupporting cellradioimmunoprecipitation assayCortexmain olfactory bulbexternal plexiform layerinternal plexiform layermitral cell layerolfactory nerve layerglomerular layerPhosphate-buffered salineMouse modelsubventricular zoneMitochondrionSubependymal zonewildtypeolfactory bulbglyceraldehyde-3-phosphate dehydrogenase
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Authors
Sabrina Schreiber, Elisabeth Petrasch-Parwez, Elke Porrmann-Kelterbaum, Eckart Förster, Jörg T. Epplen, Wanda M. Gerding,