Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10106928 | Current Opinion in Neurobiology | 2018 | 6 Pages |
Abstract
Proprioceptive sensory input and descending supraspinal projections are two major inputs that feed into and influence spinal circuitry and locomotor behaviors. Here we review their influence on each other during development and after spinal cord injury. We highlight developmental mechanisms of circuit formation as they relate to the sensory-motor circuit and its reciprocal interactions with local spinal interneurons, as well as competitive interactions between proprioceptive and descending supraspinal inputs in the setting of spinal cord injury.
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Authors
Giles W Plant, Jarret AP Weinrich, Julia A Kaltschmidt,