Article ID Journal Published Year Pages File Type
10106943 Neuroscience Letters 2018 22 Pages PDF
Abstract
The behavioral effects of ethanol in brown planarians were studied in four experiments. In the first two experiments, acute administrations of ethanol increased travel time in a dose-dependent fashion in individual planarians moving away from a light source. Orderly results were obtained using both within-subject and between-group designs. In a third experiment, ethanol dose was arranged by time rather than concentration. Ethanol increased travel time overall, but variability between subjects was considerable. In a final experiment, ethanol administration reduced motility and altered movement patterns in planarians in an open-field test. These experiments demonstrated that negative phototaxis by planarians may exhibit sufficient stability to allow for experimental determinations of dose-response curves utilizing both within-subject and between-subject designs.
Related Topics
Life Sciences Neuroscience Neuroscience (General)
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