Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10110441 | Environment International | 2018 | 12 Pages |
Abstract
Significant associations were only observed for the long AGD metrics. Positive associations were observed between MnBP or LMW phthalates and APD in males. In females, prenatal MEP was associated with a masculinizing effect on ACD, while MBzP was associated with a feminizing effect. No significant associations were observed between prenatal phenols and AGD. Given the paucity of research on digit ratios and prenatal chemical exposures, it is difficult to say whether this metric will be a useful marker of prenatal androgen or anti-androgen exposure. Given the large number of associations examined, the statistical associations observed may have been due to Type 1 error. The inconsistencies in results between studies suggest that this issue is yet to be resolved.
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Authors
Tye E. Arbuckle, Amisha Agarwal, Susan H. MacPherson, William D. Fraser, Sheela Sathyanarayana, Tim Ramsay, Linda Dodds, Gina Muckle, Mandy Fisher, Warren Foster, Mark Walker, Patricia Monnier,