Article ID Journal Published Year Pages File Type
10123777 British Journal of Anaesthesia 2005 8 Pages PDF
Abstract
These data show that both isoflurane and sevoflurane reduce apparent myofilament Ca2+ sensitivity at steady state. However, sevoflurane (but not isoflurane) induced transient changes in apparent myofilament Ca2+ sensitivity, which would contribute to its inotropic profile.
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Health Sciences Medicine and Dentistry Anesthesiology and Pain Medicine
Preview
Transient and sustained changes in myofilament sensitivity to Ca2+ contribute to the inotropic effects of sevoflurane in rat ventricle
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