Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10123797 | British Journal of Anaesthesia | 2005 | 9 Pages |
Abstract
Our study re-emphasizes the importance of a sampling site when performing PK-PD modelling for drugs undergoing elimination from the effect compartment. For a drug undergoing tissue elimination such as remifentanil, venous rather than arterial concentrations will reflect more exactly the effect compartment concentrations, under steady-state conditions.
Keywords
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Authors
Kabbaj M., Vachon P., Varin F.,