miR-143 and miR-145 promote hypoxia-induced proliferation and migration of pulmonary arterial smooth muscle cells through regulating ABCA1 expression

Article ID	Journal	Published Year	Pages	File Type
10129552	Cardiovascular Pathology	2018	11 Pages	PDF

Abstract

miR-143/145 promoted hypoxia-induced proliferation and migration of PASMCs by targeting ABCA1, contributing to better understanding of the mechanism underlying the pathogenesis of PAH.

Keywords

CCK-8 PAH ABCA1 VSMCs UTRs PASMCs ATP-binding cassette transporter A1 RNA immunoprecipitation Vascular smooth muscle cells pulmonary artery smooth muscle cells cell counting kit-8 Pulmonary arterial hypertension Hypoxia RIP

Related Topics

Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine

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miR-143 and miR-145 promote hypoxia-induced proliferation and migration of pulmonary arterial smooth muscle cells through regulating ABCA1 expression

Authors

Yuxia Yue, Zhiyong Zhang, Lei Zhang, Songhu Chen, Yilin Guo, Yan Hong,