Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10130252 | Chemosphere | 2018 | 33 Pages |
Abstract
illustrating the proposed mechanism by ATR-induced nephrotoxicity in quail. Nrf2 signaling pathway was blocked by ATR in kidney of quail. Mitochondria in quail kidney were the target organelles of ATR induced nephrotoxicity. ATR damaged mitochondrial function and morphology. It is deduced that ATR-induced nephrotoxicity is associated with mitochondrial dysfunction and interruption of Nrf2 signaling pathway.192
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Authors
Cong Zhang, Lei Qin, Da-Chang Dou, Xue-Nan Li, Jing Ge, Jin-Long Li,