A mechanistic framework for integrating chemical structure and high-throughput screening results to improve toxicity predictions

Article ID	Journal	Published Year	Pages	File Type
10137107	Computational Toxicology	2018	52 Pages	PDF

Keywords

AHR AOP Structural alert MAD MIE ToxCast Structure activity relationship (SAR)molecular initiating event Adverse outcome pathway (AOP)adverse outcome pathway median absolute deviation Adverse outcome aryl hydrocarbon receptor Estrogen receptor glucocorticoid receptor Nuclear receptor

Related Topics

Physical Sciences and Engineering Mathematics Computational Mathematics

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A mechanistic framework for integrating chemical structure and high-throughput screening results to improve toxicity predictions

Authors

Mark D. Nelms, Claire L. Mellor, Steven J. Enoch, Richard S. Judson, Grace Patlewicz, Ann M. Richard, Judith M. Madden, Mark T.D. Cronin, Stephen W. Edwards,