| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10138320 | Behavioural Brain Research | 2019 | 10 Pages |
Abstract
Results show that maternal separation lowered sucrose preference in female SERT+/â rats compared to control SERT+/â rats, reflecting anhedonic behaviour. In addition, compared to control SERT+/â rats, maternal separation significantly lowered NGF gene expression in SERT+/â rats in both BLA and PVN, but did not affect plasma corticosterone levels. Together, these results show that early-life stress in female SERT+/â rats leads to depression-like behaviour and related plasticity impairments in the BLA and PVN.
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Authors
D.J. Houwing, A.S. Ramsteijn, I.W. Riemersma, J.D.A. Olivier,