Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10140763 | Food Chemistry | 2019 | 29 Pages |
Abstract
A QuEChERS technique employing multi-walled carbon nanotubes was developed and validated for the simultaneous quantitation of boscalid and pyraclostrobin in grape field samples using rapid resolution liquid chromatography triple- quadrupole tandem mass spectrometry. The validated method was successfully applied to determine the levels of residual boscalid and pyraclostrobin in soil and grapes. The dissipation behavior of each fungicide followed first-order kinetics, with a linear correlation coefficient of 0.995-0.998 at 95% confidence. The highest levels of boscalid and pyraclostrobin in grape, with a pre-harvest interval of 14â¯days and doses of 380-570â¯mg a.i.â¯kgâ1 in three or four applications, were 3.99â¯mgâ¯kgâ1 and 0.792â¯mgâ¯kgâ1, respectively. These are below the maximum residue limits for boscalid and pyraclostrobin in grape, as recommended by the Chinese Ministry of Agriculture. Risk quotients (RQs) of these pesticides were evaluated by comparing national estimated daily intake with acceptable daily intake. The results yielded RQs for boscalid and pyraclostrobin in grape of 54% and 31.7%, respectively, which suggest a low health risk to consumers.
Keywords
PHISTMRNEDIRRLC-QqQ-MS/MSResidue distributionsupervised trials median residueLOQsMWCNTsMRLsADIRSDsDietary risk assessmentrelative standard deviationsBoscalidMaximum Residue LimitsAcceptable daily intakeGood Agricultural PracticesRisk quotientGAPPre-harvest intervalLODsLimits of quantificationlimits of detectionMulti-walled carbon nanotubesPyraclostrobin
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Xiaoxin Chen, Sheng He, Yimeng Gao, Yecheng Ma, Jiye Hu, Xiaolu Liu,