Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10144070 | Annals of Medicine and Surgery | 2018 | 26 Pages |
Abstract
Positive circumferential resection margin following APR resulted in significantly increased local recurrence with a trend towards poorer survival outcomes. Extralevator abdomino-perineal resection may have benefited some of these patients with locally advanced tumours and postero-lateral recurrences. However, this has to be balanced against exposing patients to increased risk of adverse events. We would recommend selective use of Extralevator abdominoperineal resection for locally advanced and node-positive tumours although further studies to help refine selection criteria are required with long-term follow-up.
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Authors
Anwar Hussain, Fahad Mahmood, Andrew D.W. Torrance, Helen Clarke, Cordelia Howitt, Robin Dawson,