Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10147447 | European Journal of Medicinal Chemistry | 2018 | 43 Pages |
Abstract
A series of 6,7-disubstituted-4-phenoxyquinoline derivatives bearing the 1,8-naphthyridin-2-one moiety (25-56) were designed, synthesized and evaluated for their activity against c-Met kinase and cancer cell lines. The most promising compound 33 showed excellent in vitro activity.265
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Authors
Qidong Tang, Yongli Duan, Hehua Xiong, Ting Chen, Zhen Xiao, Linxiao Wang, Yueyue Xiao, Shunmin Huang, Yinhua Xiong, Wufu Zhu, Ping Gong, Pengwu Zheng,