The influence of systemic-to-pulmonary arterial shunts and peripheral vasculatures in univentricular circulations: Focus on coronary perfusion and aortic arch hemodynamics through computational multi-domain modeling

Flow rates and pressures predicted by the patient-specific models revealed overall agreement with clinical data. Differences in the local hemodynamics were seen during diastole between the two models. Varying the three-dimensional models, while keeping an identical LPM, led to comparable flow distribution through the AA, suggesting that peripheral vasculatures have a dominant effect on local hemodynamics with respect to the shunt configuration.