| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10154431 | Journal of Chromatography A | 2018 | 28 Pages |
Abstract
In this study our preliminary attempt for obtaining fast and highly efficient separations of enantiomers in high-performance liquid chromatography with slightly modified state-of-the-art commercial instrumentation is described. In order to reach this goal after careful selection of chiral analytes, the preparation of chiral stationary phase (CSP), mobile phase composition and column dimensions were optimized. The concept of segmented chiral-achiral column was introduced. As the result of these optimizations baseline separation of enantiomers was achieved with the analysis time between 1-2âs.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Nana Khundadze, Salome Pantsulaia, Chiara Fanali, Tivadar Farkas, Bezhan Chankvetadze,