Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10156264 | Journal of Environmental Radioactivity | 2018 | 7 Pages |
Abstract
In this study, we investigated the association between depression, anxiety and medication adherence in patients with arterial hypertension living in East Kazakhstan region. The sample size included 795 patients, of whom 403 patients were exposed to radiation at the Semipalatinsk Nuclear Test Site from 1949 to 1989, while 395 patients were unexposed to radiation due to their very remote residence from the Site at the same period. Both exposed and unexposed patients showed no significant differences concerning body mass index, smoking habit, the presence of hypercholesterolemia, and hypertension grade. Patients with arterial hypertension previously exposed to radiation had significantly higher rates of low medication adherence, subclinical and clinical depression, situational anxiety of moderate and severe grade, and personal anxiety of moderate grade. A logistic regression analysis allowed us to identify the presence of significant positive association between medication adherence and anxiety in exposed patients (ORâ¯=â¯4041 (95%CI:1709-9556) pâ¯=â¯0.001) and marginal association (ORâ¯=â¯2998 (95%CI:1008-8915) pâ¯=â¯0.048) between the same parameters in unexposed patients. It might prove to be useful to introduce psychological and medical counseling with an emphasis on strengthening of medication adherence and to inform the local population about radiation effects and dosimetry data.
Related Topics
Physical Sciences and Engineering
Energy
Nuclear Energy and Engineering
Authors
Lyazzat Dyussenova, Lyudmila Pivina, Yuliya Semenova, Geir Bjørklund, Natalia Glushkova, Salvatore Chirumbolo, Tatyana Belikhina,