| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10157451 | Biology of Blood and Marrow Transplantation | 2018 | 27 Pages |
Abstract
- We studied the effects of fotemustine substitution in BEAM, prompted by BCNU shortage.
- BEAM and FEAM did not appear different in terms of survival and disease control.
- FEAM resulted in higher rates of gastrointestinal and infectious toxicities.
- Mortality from infection was higher with FEAM, due to more sepsis from Gram-negative bacteria.
- FEAM is an acceptable alternative to BEAM but is not justified when BCNU is available.
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Authors
Jacopo Olivieri, Federico Mosna, Matteo Pelosini, Angelo Fama, Sara Rattotti, Margherita Giannoccaro, Giuseppe Carli, Maria Chiara Tisi, Simone Ferrero, Nicola Sgherza, Anna Maria Mazzone, Dario Marino, Teresa Calimeri, Giacomo Loseto,